Last reviewed · How we verify
Antizol — Competitive Intelligence Brief
marketed
Antidote [EPC]
Alcohol dehydrogenase
Metabolic
Small molecule
Live · refreshed every 30 min
Target snapshot
Antizol (FOMEPIZOLE) — Par Pharm Inc. Antizol works by competitively inhibiting the enzyme alcohol dehydrogenase, which is responsible for converting toxic alcohols into their more toxic metabolites.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Antizol TARGET | FOMEPIZOLE | Par Pharm Inc | marketed | Antidote [EPC] | Alcohol dehydrogenase | 1997-01-01 |
| Depakene | valproic acid | Generic (originally Abbott/AbbVie) | marketed | Anti-epileptic Agent [EPC] | Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2 | 1978-02-28 |
| Divalproex | Divalproex | University of Chicago | marketed | Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2 | ||
| Antizol | Antizol | Amgen | marketed | Alcohol dehydrogenase, Alcohol dehydrogenase | ||
| Epilim | sodium valproate | Sanofi | marketed | Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2 | ||
| Cyanokit | HYDROXOCOBALAMIN | Btg Intl | marketed | Antidote | 1978-01-01 | |
| Acetadote | Acetylcysteine | Bristol-Myers Squibb | marketed | Antidote | Glutathione levels; reactive metabolite of acetaminophen | 1963-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Acetadote · 8148356 · Formulation · US
- — Acetadote · 9327028 · Method of Use · US
- — Acetadote · 8722738 · Method of Use · US
- — Acetadote · 8747894 · Formulation · US
- — Acetadote · 9561204 · Method of Use · US
- — Acetadote · 9427421 · Formulation · US
Sponsor landscape (Antidote [EPC] class)
- New York State Institute for Basic Research · 1 drug in this class
- Par Pharm Inc · 1 drug in this class
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- Antizol CI watch — RSS
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- Whole Antidote [EPC] class — RSS
Cite this brief
Drug Landscape (2026). Antizol — Competitive Intelligence Brief. https://druglandscape.com/ci/fomepizole. Accessed 2026-05-13.
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