Who are FOLFOX4 or XELOX's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): S-1 plus CDDP, CAPOXIRI, CAPOX chemotherapy.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/folfox4-or-xelox.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-16 · How we verify

FOLFOX4 or XELOX — Competitive Intelligence Brief

FOLFOX4 or XELOX (FOLFOX4 or XELOX) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy (fluoropyrimidine + platinum agent). Area: Oncology.

phase 3 Combination chemotherapy (fluoropyrimidine + platinum agent) Thymidylate synthase (5-FU/capecitabine); DNA (oxaliplatin cross-linking) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FOLFOX4 or XELOX (FOLFOX4 or XELOX) — Federation Francophone de Cancerologie Digestive. FOLFOX4 and XELOX are combination chemotherapy regimens that inhibit DNA synthesis and cell division through fluoropyrimidine and platinum-based cytotoxic agents.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
FOLFOX4 or XELOX TARGET	FOLFOX4 or XELOX	Federation Francophone de Cancerologie Digestive	phase 3	Combination chemotherapy (fluoropyrimidine + platinum agent)	Thymidylate synthase (5-FU/capecitabine); DNA (oxaliplatin cross-linking)
S-1 plus CDDP	S-1 plus CDDP	Taiho Pharmaceutical Co., Ltd.	phase 3	Combination chemotherapy (fluoropyrimidine + platinum agent)	Thymidylate synthase (S-1); DNA (CDDP)
CAPOXIRI	CAPOXIRI	National Cancer Center Hospital East	phase 3	Combination chemotherapy (fluoropyrimidine + platinum agent)	Thymidylate synthase (capecitabine); DNA (oxaliplatin cross-linking)
CAPOX chemotherapy	CAPOX chemotherapy	Sun Yat-sen University	phase 3	Combination chemotherapy (fluoropyrimidine + platinum agent)	Thymidylate synthase (capecitabine/5-FU); DNA (oxaliplatin)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy (fluoropyrimidine + platinum agent) class)

Federation Francophone de Cancerologie Digestive · 1 drug in this class
National Cancer Center Hospital East · 1 drug in this class
Sun Yat-sen University · 1 drug in this class
Taiho Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FOLFOX4 or XELOX — Competitive Intelligence Brief. https://druglandscape.com/ci/folfox4-or-xelox. Accessed 2026-05-16.

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