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FOLFOX or — Competitive Intelligence Brief

FOLFOX or (FOLFOX or) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Thymidylate synthase (5-FU); DNA (oxaliplatin) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FOLFOX or (FOLFOX or) — Alliance for Clinical Trials in Oncology. FOLFOX is a chemotherapy regimen combining 5-fluorouracil, leucovorin, and oxaliplatin to inhibit DNA synthesis and cross-link DNA in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
FOLFOX or TARGET FOLFOX or Alliance for Clinical Trials in Oncology phase 3 Combination chemotherapy regimen Thymidylate synthase (5-FU); DNA (oxaliplatin)
SOX Chemotherapy SOX Chemotherapy The First Affiliated Hospital with Nanjing Medical University marketed Combination chemotherapy regimen
CEV chemotherapy CEV chemotherapy Sun Yat-sen University marketed Combination chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI chemotherapy of mFOLFOX6 or FOLFIRI Xu jianmin marketed Combination chemotherapy regimen Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
PTH followed by dose dense AC of FEC PTH followed by dose dense AC of FEC Agendia marketed Combination chemotherapy regimen with monoclonal antibody HER2 receptor; microtubule; DNA (topoisomerase II)
FEC FEC Hoffmann-La Roche marketed Combination chemotherapy regimen
Consolidation Chemotherapy Consolidation Chemotherapy National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos marketed Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

  1. Sun Yat-sen University · 5 drugs in this class
  2. Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
  3. Hoffmann-La Roche · 2 drugs in this class
  4. University Hospital, Bordeaux · 2 drugs in this class
  5. Beijing Friendship Hospital · 1 drug in this class
  6. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  7. Amgen · 1 drug in this class
  8. Chungnam National University Hospital · 1 drug in this class
  9. AstraZeneca · 1 drug in this class
  10. Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FOLFOX or — Competitive Intelligence Brief. https://druglandscape.com/ci/folfox-or. Accessed 2026-05-13.

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