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FOFLOX4 — Competitive Intelligence Brief

FOFLOX4 (FOFLOX4) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Thymidylate synthase (5-FU); DNA (oxaliplatin) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FOFLOX4 (FOFLOX4) — Guangdong Provincial People's Hospital. FOFLOX4 is a chemotherapy regimen combining fluorouracil, folinic acid (leucovorin), and oxaliplatin to inhibit DNA synthesis and induce apoptosis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
FOFLOX4 TARGET FOFLOX4 Guangdong Provincial People's Hospital phase 3 Combination chemotherapy regimen Thymidylate synthase (5-FU); DNA (oxaliplatin)
PTH followed by dose dense AC of FEC PTH followed by dose dense AC of FEC Agendia marketed Combination chemotherapy regimen with monoclonal antibody HER2 receptor; microtubule; DNA (topoisomerase II)
CVP CVP SCRI Development Innovations, LLC marketed Combination chemotherapy regimen
FEC FEC Hoffmann-La Roche marketed Combination chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI chemotherapy of mFOLFOX6 or FOLFIRI Xu jianmin marketed Combination chemotherapy regimen Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
CEV chemotherapy CEV chemotherapy Sun Yat-sen University marketed Combination chemotherapy regimen
SOX Chemotherapy SOX Chemotherapy The First Affiliated Hospital with Nanjing Medical University marketed Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

  1. Sun Yat-sen University · 5 drugs in this class
  2. Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
  3. Hoffmann-La Roche · 2 drugs in this class
  4. University Hospital, Bordeaux · 2 drugs in this class
  5. Beijing Friendship Hospital · 1 drug in this class
  6. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  7. Amgen · 1 drug in this class
  8. Chungnam National University Hospital · 1 drug in this class
  9. AstraZeneca · 1 drug in this class
  10. Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FOFLOX4 — Competitive Intelligence Brief. https://druglandscape.com/ci/foflox4. Accessed 2026-05-13.

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