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Fluorouracil implant — Competitive Intelligence Brief
phase 3
Antimetabolite chemotherapy agent
Thymidylate synthase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Fluorouracil implant (Fluorouracil implant) — Austrian Breast & Colorectal Cancer Study Group. Fluorouracil implant delivers the chemotherapy agent 5-fluorouracil directly to tumor tissue to inhibit thymidylate synthase and disrupt DNA synthesis in cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Fluorouracil implant TARGET | Fluorouracil implant | Austrian Breast & Colorectal Cancer Study Group | phase 3 | Antimetabolite chemotherapy agent | Thymidylate synthase | |
| Xeloda | capecitabine | Cheplapharm | marketed | Nucleoside Metabolic Inhibitor [EPC] | Thymidylate synthase | 1998-01-01 |
| Fudr | FLOXURIDINE | marketed | Antimetabolite [EPC] | Thymidylate synthase | 1970-01-01 | |
| Folic Acid | FOLIC ACID | Pfizer | marketed | Vitamin C [EPC] | Thymidylate synthase | 1946-01-01 |
| Fluorouracil Injection | Fluorouracil Injection | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | marketed | Antimetabolite | Thymidylate synthase | |
| Anlotinib plus Pemetrexed | Anlotinib plus Pemetrexed | Henan Provincial People's Hospital | marketed | Multi-target tyrosine kinase inhibitor plus antifolate antimetabolite | VEGFR, FGFR, RET, c-Kit (anlotinib); thymidylate synthase, DHFR, GARFT (pemetrexed) | |
| 5-Fluorouracile | 5-Fluorouracile | Groupe Oncologie Radiotherapie Tete et Cou | marketed | Antimetabolite; pyrimidine analog | Thymidylate synthase; RNA and DNA incorporation |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antimetabolite chemotherapy agent class)
- Austrian Breast & Colorectal Cancer Study Group · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Fluorouracil implant — Competitive Intelligence Brief. https://druglandscape.com/ci/fluorouracil-implant. Accessed 2026-05-16.
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