Who are FLOT chemotherapy's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): SOX Chemotherapy, CVP, chemotherapy of mFOLFOX6 or FOLFIRI, Carboplatin, Etoposide, Ifosfamide, Dexamethasona, Idarubicine, ARA-C, Methotrexate, Consolidation Chemotherapy.

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Last reviewed 2026-06-10 · How we verify

FLOT chemotherapy — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

FLOT chemotherapy (FLOT chemotherapy) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

FLOT chemotherapy (FLOT chemotherapy) — AstraZeneca. FLOT is a combination chemotherapy regimen that uses four cytotoxic agents to inhibit cancer cell division and induce apoptosis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
FLOT chemotherapy TARGET	FLOT chemotherapy	AstraZeneca	phase 3	Combination chemotherapy regimen
SOX Chemotherapy	SOX Chemotherapy	The First Affiliated Hospital with Nanjing Medical University	marketed	Combination chemotherapy regimen
CVP	CVP	SCRI Development Innovations, LLC	marketed	Combination chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI	chemotherapy of mFOLFOX6 or FOLFIRI	Xu jianmin	marketed	Combination chemotherapy regimen	Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
Carboplatin, Etoposide, Ifosfamide	Carboplatin, Etoposide, Ifosfamide	University Hospital Muenster	marketed	Combination chemotherapy regimen	DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)
Dexamethasona, Idarubicine, ARA-C, Methotrexate	Dexamethasona, Idarubicine, ARA-C, Methotrexate	PETHEMA Foundation	marketed	Combination chemotherapy regimen
Consolidation Chemotherapy	Consolidation Chemotherapy	National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos	marketed	Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

Sun Yat-sen University · 5 drugs in this class
Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
Hoffmann-La Roche · 2 drugs in this class
University Hospital, Bordeaux · 2 drugs in this class
Beijing Friendship Hospital · 1 drug in this class
Centre Hospitalier Universitaire Dijon · 1 drug in this class
Amgen · 1 drug in this class
Chungnam National University Hospital · 1 drug in this class
AstraZeneca · 1 drug in this class
Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). FLOT chemotherapy — Competitive Intelligence Brief. https://druglandscape.com/ci/flot-chemotherapy. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing