Who are Eylea® Solution for intravitreal injection's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Ziv aflibercept, Deferred aflibercept, Prompt aflibercept, Eylea HD (aflibercept HD).

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Eylea® Solution for intravitreal injection — Competitive Intelligence Brief

Eylea® Solution for intravitreal injection (Eylea® Solution for intravitreal injection) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: VEGF inhibitor / Antiangiogenic agent. Area: Ophthalmology.

phase 3 VEGF inhibitor / Antiangiogenic agent VEGF-A, VEGF-B, PlGF (placental growth factor) Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Eylea® Solution for intravitreal injection (Eylea® Solution for intravitreal injection) — Rophibio, Inc.. Eylea (aflibercept) binds to vascular endothelial growth factor (VEGF) and placental growth factor (PlGF) to inhibit abnormal blood vessel growth in the eye.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Eylea® Solution for intravitreal injection TARGET	Eylea® Solution for intravitreal injection	Rophibio, Inc.	phase 3	VEGF inhibitor / Antiangiogenic agent	VEGF-A, VEGF-B, PlGF (placental growth factor)
Ziv aflibercept	Ziv aflibercept	Marashi Eye Clinic	marketed	VEGF inhibitor / Antiangiogenic agent	VEGF-A, VEGF-B, PlGF (Placental Growth Factor)
Deferred aflibercept	Deferred aflibercept	Jaeb Center for Health Research	phase 3	VEGF inhibitor / Antiangiogenic agent	VEGF (vascular endothelial growth factor), PlGF (placental growth factor)
Prompt aflibercept	Prompt aflibercept	Jaeb Center for Health Research	phase 3	VEGF inhibitor / Antiangiogenic agent	VEGF (vascular endothelial growth factor), PlGF (placental growth factor)
Eylea HD (aflibercept HD)	Eylea HD (aflibercept HD)	Alvotech Swiss AG	phase 3	VEGF inhibitor / Antiangiogenic agent	VEGF-A, PlGF (Placental Growth Factor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (VEGF inhibitor / Antiangiogenic agent class)

Jaeb Center for Health Research · 2 drugs in this class
Alvotech Swiss AG · 1 drug in this class
Marashi Eye Clinic · 1 drug in this class
Rophibio, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Eylea® Solution for intravitreal injection — Competitive Intelligence Brief. https://druglandscape.com/ci/eylea-solution-for-intravitreal-injection. Accessed 2026-05-14.

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