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Etoposide, carboplatin, melphalan, cisplatin, thiotepa — Competitive Intelligence Brief
phase 2
alkylating agents
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Etoposide, carboplatin, melphalan, cisplatin, thiotepa (Etoposide, carboplatin, melphalan, cisplatin, thiotepa) — Gustave Roussy, Cancer Campus, Grand Paris. Etoposide, carboplatin, melphalan, cisplatin, and thiotepa are chemotherapeutic agents that work by interfering with DNA replication and cell division, ultimately leading to cell death.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Etoposide, carboplatin, melphalan, cisplatin, thiotepa TARGET | Etoposide, carboplatin, melphalan, cisplatin, thiotepa | Gustave Roussy, Cancer Campus, Grand Paris | phase 2 | alkylating agents | ||
| Busulfan/Cyclophosphamide | Busulfan/Cyclophosphamide | Tel-Aviv Sourasky Medical Center | marketed | Alkylating agents | ||
| PCV chemotherapy | PCV chemotherapy | Hospices Civils de Lyon | phase 3 | Chemotherapy regimen (alkylating agents + vinca alkaloid) | ||
| Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan | Etoposide, Thioguanine, Cyclophosphamide, Busulfan, Melphalan | Dutch Childhood Oncology Group | phase 3 | Multi-agent chemotherapy regimen; alkylating agents, antimetabolite, topoisomerase II inhibitor | ||
| Busulphan plus Cyclophosphamide | Busulphan plus Cyclophosphamide | Gruppo Italiano Trapianto di Midollo Osseo | phase 3 | Alkylating agents | ||
| Fludarabine, OKT3, Treosulfan, Thiotepa | Fludarabine, OKT3, Treosulfan, Thiotepa | St. Anna Kinderkrebsforschung | phase 3 | Multi-agent conditioning regimen (purine analog, monoclonal antibody, alkylating agents) | dTMP synthase (fludarabine); CD3 (OKT3); DNA (treosulfan, thiotepa) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (alkylating agents class)
- Gustave Roussy, Cancer Campus, Grand Paris · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Etoposide, carboplatin, melphalan, cisplatin, thiotepa — Competitive Intelligence Brief. https://druglandscape.com/ci/etoposide-carboplatin-melphalan-cisplatin-thiotepa. Accessed 2026-05-18.
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