Who are Estradiol Vaginal Cream, 0.01%'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Estrace® Vaginal Cream USP, 0.01%.

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Last reviewed 2026-05-18 · How we verify

Estradiol Vaginal Cream, 0.01% — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Estradiol Vaginal Cream, 0.01% (Estradiol Vaginal Cream, 0.01%) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Estrogen replacement therapy (local/vaginal). Area: Gynecology / Menopause.

phase 3 Estrogen replacement therapy (local/vaginal) Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) Gynecology / Menopause Small molecule Live · refreshed every 30 min

Target snapshot

Estradiol Vaginal Cream, 0.01% (Estradiol Vaginal Cream, 0.01%) — Mylan Pharmaceuticals Inc. Estradiol vaginal cream delivers the hormone estrogen directly to vaginal tissues to relieve symptoms of vaginal atrophy and genitourinary syndrome of menopause.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Estradiol Vaginal Cream, 0.01% TARGET	Estradiol Vaginal Cream, 0.01%	Mylan Pharmaceuticals Inc	phase 3	Estrogen replacement therapy (local/vaginal)	Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
Estrace® Vaginal Cream USP, 0.01%	Estrace® Vaginal Cream USP, 0.01%	Actavis Inc.	phase 3	Estrogen replacement therapy (local/vaginal)	Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Estrogen replacement therapy (local/vaginal) class)

Actavis Inc. · 1 drug in this class
Mylan Pharmaceuticals Inc · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Estradiol Vaginal Cream, 0.01% — Competitive Intelligence Brief. https://druglandscape.com/ci/estradiol-vaginal-cream-0-01. Accessed 2026-05-18.

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