Who are Esketamine DPI - low dose's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Namenda, Felbatol, QUINIDINE, Methadone Hydrochloride, continuous infusion of intravenous ketamine, MgSO4 plus Ropivacaine.

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Last reviewed 2026-06-10 · How we verify

Esketamine DPI - low dose — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Esketamine DPI - low dose (Esketamine DPI - low dose) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NMDA receptor antagonist. Area: Psychiatry / Neurology.

phase 2 NMDA receptor antagonist NMDA receptor Psychiatry / Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Esketamine DPI - low dose (Esketamine DPI - low dose) — Celon Pharma SA. Esketamine is an NMDA receptor antagonist that blocks glutamate signaling in the brain, with rapid-acting antidepressant effects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Esketamine DPI - low dose TARGET	Esketamine DPI - low dose	Celon Pharma SA	phase 2	NMDA receptor antagonist	NMDA receptor
Namenda	MEMANTINE	AbbVie	marketed	N-methyl-D-aspartate Receptor Antagonist	Glutamate NMDA receptor; GRIN1/GRIN2A	2003-01-01
Felbatol	FELBAMATE	Mylan Speciality Lp	marketed	Anti-epileptic Agent [EPC]	NMDA receptor-ionophore complex	1993-01-01
QUINIDINE	QUINIDINE		marketed		sigma-1 receptor, NMDA receptor, CYP2D6	1950-01-01
Methadone Hydrochloride	METHADONE	Specgx Llc	marketed	Opioid Agonist	mu-opioid receptors, NMDA receptor	1947-01-01
continuous infusion of intravenous ketamine	continuous infusion of intravenous ketamine	Ciusss de L'Est de l'Île de Montréal	marketed	NMDA receptor antagonist	NMDA receptor
MgSO4 plus Ropivacaine	MgSO4 plus Ropivacaine	Hospital Universiti Sains Malaysia	marketed	Local anesthetic adjuvant combination	Voltage-gated sodium channels (ropivacaine); NMDA receptors and calcium channels (magnesium sulfate)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NMDA receptor antagonist class)

Turku University Hospital · 3 drugs in this class
H. Lundbeck A/S · 2 drugs in this class
Ciusss de L'Est de l'Île de Montréal · 2 drugs in this class
Shalvata Mental Health Center · 2 drugs in this class
New York State Psychiatric Institute · 2 drugs in this class
Auris Medical AG · 1 drug in this class
AstraZeneca · 1 drug in this class
Alameda Health System · 1 drug in this class
Centre Hospitalier Universitaire de Nice · 1 drug in this class
Asker & Baerum Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Esketamine DPI - low dose — Competitive Intelligence Brief. https://druglandscape.com/ci/esketamine-dpi-low-dose. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing