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Eptacog alfa (NovoSeven) — Competitive Intelligence Brief
marketed
Recombinant coagulation factor
Tissue factor (TF) / Factor X
Hematology
Small molecule
Live · refreshed every 30 min
Target snapshot
Eptacog alfa (NovoSeven) (Eptacog alfa (NovoSeven)) — Novo Nordisk A/S. Eptacog alfa is a recombinant Factor VIIa that bypasses upstream coagulation defects by directly activating Factor X on the tissue factor pathway to initiate thrombin generation and hemostasis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Eptacog alfa (NovoSeven) TARGET | Eptacog alfa (NovoSeven) | Novo Nordisk A/S | marketed | Recombinant coagulation factor | Tissue factor (TF) / Factor X | |
| FIX | FIX | Bioverativ Therapeutics Inc. | marketed | Recombinant coagulation factor replacement | Factor IX (coagulation cascade) | |
| Kogenate (BAY14-2222) | Kogenate (BAY14-2222) | Bayer | marketed | Recombinant coagulation factor VIII | Coagulation factor VIII | |
| Intravenous infusions of Xyntha | Intravenous infusions of Xyntha | Pfizer | marketed | Recombinant coagulation factor VIII | Coagulation factor VIII | |
| Moroctocog alfa (AF-CC) | Moroctocog alfa (AF-CC) | Pfizer | marketed | Recombinant coagulation factor VIII | Coagulation factor VIII | |
| RIXUBIS: On-Demand | RIXUBIS: On-Demand | Baxalta now part of Shire | marketed | Recombinant coagulation factor | Coagulation Factor IX (FIX) | |
| Kogenate (BAY 14-2222) | Kogenate (BAY 14-2222) | Bayer | marketed | Recombinant coagulation factor VIII | Coagulation factor VIII |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Recombinant coagulation factor class)
- Baxalta now part of Shire · 2 drugs in this class
- AryoGen Pharmed Co. · 1 drug in this class
- Nicoletta C Machin · 1 drug in this class
- Novo Nordisk A/S · 1 drug in this class
- ZymoGenetics · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Eptacog alfa (NovoSeven) — Competitive Intelligence Brief. https://druglandscape.com/ci/eptacog-alfa-novoseven. Accessed 2026-05-16.
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