Last reviewed · How we verify
epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile — Competitive Intelligence Brief
Target snapshot
epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile (epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile) — Sanofi. Epidoxorubicine is an anthracycline antibiotic that intercalates DNA strands, thereby inhibiting the progression of topoisomerase II and inducing apoptosis in cancer cells. Docetaxel is a taxane that stabilizes microtubules, preventing cell division and leading to cell death. Ciclophosphamide is an alkylating agent that adds an alkyl group to DNA, causing cross-linking and DNA damage. Methotrexate is an antifolate that inhibits dihydrofolate reductase, leading to a decrease in DNA synthesis and cell proliferation. Fluorouracile is a thymidylate synthase inhibitor that disrupts DNA synthesis and repair.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile TARGET | epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile | Sanofi | phase 3 | anthracycline antibiotic, taxane, alkylating agent, antifolate, thymidylate synthase inhibitor | topoisomerase II, microtubules, dihydrofolate reductase, thymidylate synthase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (anthracycline antibiotic, taxane, alkylating agent, antifolate, thymidylate synthase inhibitor class)
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). epidoxorubicine, docetaxel, ciclophosphamide, methotrexate, fluorouracile — Competitive Intelligence Brief. https://druglandscape.com/ci/epidoxorubicine-docetaxel-ciclophosphamide-methotrexate-fluorouracile. Accessed 2026-05-17.
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