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Last reviewed 2026-05-17 · How we verify

epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile (epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: anthracycline antibiotic. Area: Oncology.

phase 3 anthracycline antibiotic topoisomerase II Oncology Small molecule Live · refreshed every 30 min

Target snapshot

epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile (epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile) — Sanofi. Epidoxorubicine is an anthracycline antibiotic that intercalates DNA strands, thereby inhibiting the progression of topoisomerase II and inducing apoptosis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile TARGET	epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile	Sanofi	phase 3	anthracycline antibiotic	topoisomerase II
Idamycin Pfs	Idarubicin Hydrochloride	Pfizer Inc.	marketed	Anthracycline topoisomerase inhibitor	DNA, Topoisomerase II	1990-01-01
Idamycin Pfs	IDARUBICIN HYDROCHLORIDE		marketed	Anthracycline Topoisomerase Inhibitor	DNA, topoisomerase II	1990-01-01
Idamycin Pfs	Idarubicin Hydrochloride	Pfizer Inc.	marketed	Anthracycline topoisomerase inhibitor	DNA, Topoisomerase II	1990-01-01
Cipro	ciprofloxacin	Bayer AG	marketed	Fluoroquinolone antibiotic	DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A	1987-10-22
Amekrin	AMSACRINE		marketed	amsacrine	DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II	1987-01-01
DOXORUBICIN HYDROCHLORIDE	DOXORUBICIN HYDROCHLORIDE		marketed		topoisomerase II	1974-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-04-21 — Cipro · 11369566 · Formulation · US
2029-04-21 — Cipro · 9603796 · Compound · US
2029-04-21 — Cipro · 9205048 · Method of Use · US
2029-12-11 — Cipro · 9233068 · Formulation · US
2030-04-27 — Cipro · 8318817 · Method of Use · US
2035-07-01 — Cipro · 9220796 · Formulation · US
2037-11-12 — Cipro · 11040004 · Method of Use · US
2038-11-27 — Cipro · 11246863 · Formulation · US

Sponsor landscape (anthracycline antibiotic class)

Cephalon, Inc. · 1 drug in this class
Gruppo Italiano Malattie EMatologiche dell'Adulto · 1 drug in this class
Sanofi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). epidoxorubicine, ciclophosphamide, methotrexate, fluorouracile — Competitive Intelligence Brief. https://druglandscape.com/ci/epidoxorubicine-ciclophosphamide-methotrexate-fluorouracile. Accessed 2026-05-17.

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