Who are EN3267's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): MP-513, LJPC-501, HBM9036 0.25% Ophthalmic Solution, FK199B, KK8398.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

EN3267 — Competitive Intelligence Brief

EN3267 (EN3267) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: C5a receptor antagonist. Area: Immunology.

phase 3 C5a receptor antagonist C5aR1 (C5a receptor 1) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

EN3267 (EN3267) — Kyowa Kirin Co., Ltd.. EN3267 is a complement C5a receptor antagonist that blocks the C5a-C5aR1 axis to reduce inflammatory cell recruitment and activation.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
EN3267 TARGET	EN3267	Kyowa Kirin Co., Ltd.	phase 3	C5a receptor antagonist	C5aR1 (C5a receptor 1)
MP-513	MP-513	Tanabe Pharma Corporation	phase 3	Complement C5a receptor antagonist	C5a receptor (C5aR)
LJPC-501	LJPC-501	La Jolla Pharmaceutical Company	phase 3	Complement C5a receptor antagonist	C5a receptor (C5aR)
HBM9036 0.25% Ophthalmic Solution	HBM9036 0.25% Ophthalmic Solution	Harbour BioMed (Guangzhou) Co. Ltd.	phase 3	C5a receptor antagonist	C5aR (C5a receptor)
FK199B	FK199B	Astellas Pharma Inc	phase 3	C5a receptor antagonist	C5a receptor (C5aR)
KK8398	KK8398	Kyowa Kirin Co., Ltd.	phase 3	Complement C5a receptor antagonist	C5aR1 (C5a receptor 1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (C5a receptor antagonist class)

Astellas Pharma Inc · 2 drugs in this class
Astellas Pharma Europe B.V. · 1 drug in this class
Harbour BioMed (Guangzhou) Co. Ltd. · 1 drug in this class
Kyowa Kirin Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). EN3267 — Competitive Intelligence Brief. https://druglandscape.com/ci/en3267. Accessed 2026-05-13.

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