Who are Trikafta (Copackaged)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Kalydeco, Kalydeco, SUZ, TEZ, Ivacaftor and Symdeko, Ivacaftor/Ataluren.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

Trikafta (Copackaged) — Competitive Intelligence Brief

Trikafta (Copackaged) (ELEXACAFTOR) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Area: Respiratory.

marketed Cystic fibrosis transmembrane conductance regulator Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Trikafta (Copackaged) (ELEXACAFTOR) — Vertex Pharms Inc. Trikafta works by correcting the faulty protein that causes cystic fibrosis, allowing the body to produce normal amounts of mucus.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Trikafta (Copackaged) TARGET	ELEXACAFTOR	Vertex Pharms Inc	marketed		Cystic fibrosis transmembrane conductance regulator	2019-01-01
Kalydeco	IVACAFTOR	Vertex Pharms Inc	marketed	Cystic Fibrosis Transmembrane Conductance Regulator Potentiator [EPC]	Cystic fibrosis transmembrane conductance regulator	2012-01-01
Kalydeco	Kalydeco	Concert Pharmaceuticals	marketed		Cystic fibrosis transmembrane conductance regulator
SUZ	SUZ	Vertex Pharmaceuticals Incorporated	marketed	CFTR potentiator	CFTR (cystic fibrosis transmembrane conductance regulator)
TEZ	TEZ	Vertex Pharmaceuticals Incorporated	marketed	CFTR corrector	CFTR (cystic fibrosis transmembrane conductance regulator)
Ivacaftor and Symdeko	Ivacaftor and Symdeko	University of Alabama at Birmingham	marketed	CFTR modulator (potentiator and corrector combination)	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)
Ivacaftor/Ataluren	Ivacaftor/Ataluren	University of Alabama at Birmingham	marketed	CFTR modulator combination	CFTR (Cystic Fibrosis Transmembrane Conductance Regulator)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-07-06 — Trikafta (Copackaged) · 8354427 · US
2026-12-28 — Trikafta (Copackaged) · 8410274 · US
2026-12-28 — Trikafta (Copackaged) · 9931334 · US
2026-12-28 — Trikafta (Copackaged) · 9670163 · US
2026-12-28 — Trikafta (Copackaged) · 8754224 · US
2027-04-09 — Trikafta (Copackaged) · 10239867 · US
2027-04-09 — Trikafta (Copackaged) · 9974781 · US
2027-04-09 — Trikafta (Copackaged) · 11639347 · US
2027-04-09 — Trikafta (Copackaged) · 10022352 · US
2027-05-01 — Trikafta (Copackaged) · 7645789 · US
2027-05-01 — Trikafta (Copackaged) · 8598181 · US
2027-05-01 — Trikafta (Copackaged) · 8623905 · US
2027-05-20 — Trikafta (Copackaged) · 7495103 · US
2027-06-03 — Trikafta (Copackaged) · 7776905 · US
2027-08-05 — Trikafta (Copackaged) · 8324242 · US
2027-11-12 — Trikafta (Copackaged) · 8415387 · US
2029-08-13 — Trikafta (Copackaged) · 10646481 · US
2029-08-13 — Trikafta (Copackaged) · 11564916 · US
2031-03-25 — Trikafta (Copackaged) · 11578062 · US
2031-03-25 — Trikafta (Copackaged) · 10081621 · US
2033-02-27 — Trikafta (Copackaged) · 8883206 · US
2033-02-27 — Trikafta (Copackaged) · 11147770 · US
2033-02-27 — Trikafta (Copackaged) · 10272046 · US
2033-07-15 — Trikafta (Copackaged) · 9012496 · US
2035-10-06 — Trikafta (Copackaged) · 11426407 · US
2035-10-06 — Trikafta (Copackaged) · 10758534 · US
2037-12-08 — Trikafta (Copackaged) · 11517564 · US
2037-12-08 — Trikafta (Copackaged) · 11453655 · US
2037-12-08 — Trikafta (Copackaged) · 10793547 · US
2037-12-08 — Trikafta (Copackaged) · 11179367 · US

Sponsor landscape

No sponsor landscape data.

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Cite this brief

Drug Landscape (2026). Trikafta (Copackaged) — Competitive Intelligence Brief. https://druglandscape.com/ci/elexacaftor. Accessed 2026-05-15.

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