Who are H5G1.1's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Veopoz, Izervay, AVACINCAPTAD PEGOL SODIUM, Tavneos, Ultomiris, Ro 205720.

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Last reviewed 2026-05-14 · How we verify

H5G1.1 — Competitive Intelligence Brief

H5G1.1 (ECULIZUMAB) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Complement Inhibitor [EPC]. Area: Neuroscience.

marketed Complement Inhibitor [EPC] C5 Neuroscience Monoclonal antibody Live · refreshed every 30 min

Target snapshot

H5G1.1 (ECULIZUMAB) — AstraZeneca. Eculizumab-aeeb binds to complement protein C5, inhibiting its cleavage and preventing terminal complement complex formation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
H5G1.1 TARGET	ECULIZUMAB	AstraZeneca	marketed	Complement Inhibitor [EPC]	C5	2007-01-01
Veopoz	POZELIMAB	Regeneron	marketed	Complement Inhibitor [EPC]	Complement C5	2023-01-01
Izervay	AVACINCAPTAD PEGOL	Astellas Pharma	marketed		Complement C5	2023-01-01
AVACINCAPTAD PEGOL SODIUM	AVACINCAPTAD PEGOL SODIUM		marketed	Complement Inhibitors	Complement C5	2023-01-01
Tavneos	AVACOPAN	Chemocentryx	marketed	Complement 5a Receptor Antagonist [EPC]	C5a anaphylatoxin chemotactic receptor 1	2021-01-01
Ultomiris	RAVULIZUMAB	AstraZeneca	marketed	Complement Inhibitor [EPC]	Complement C5	2018-01-01
Ro 205720	CARPROFEN	Roche	marketed	carprofen	Complement C5, Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2	1987-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-11-11 — AVACINCAPTAD PEGOL SODIUM · 8236773 · Method of Use · US
2027-02-14 — AVACINCAPTAD PEGOL SODIUM · 9617546 · Compound · US
2027-02-14 — AVACINCAPTAD PEGOL SODIUM · 7579456 · Compound · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 11491176 · Method of Use · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 11273171 · Method of Use · US
2034-07-11 — AVACINCAPTAD PEGOL SODIUM · 12016875 · Method of Use · US

Sponsor landscape (Complement Inhibitor [EPC] class)

AstraZeneca · 2 drugs in this class
AMGEN INC · 1 drug in this class
REGENERON PHARMACEUTICALS · 1 drug in this class
Regeneron · 1 drug in this class
SAMSUNG BIOEPIS CO LTD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). H5G1.1 — Competitive Intelligence Brief. https://druglandscape.com/ci/eculizumab. Accessed 2026-05-14.

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