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DT-101 — Competitive Intelligence Brief

DT-101 (DT-101) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CDK4/6 inhibitor. Area: Oncology.

phase 2 CDK4/6 inhibitor CDK4/6 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

DT-101 (DT-101) — Draig Therapeutics Ltd. DT-101 is a small molecule that targets the CDK4/6 pathway.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DT-101 TARGET DT-101 Draig Therapeutics Ltd phase 2 CDK4/6 inhibitor CDK4/6
Ibrance Palbociclib Pfizer marketed CDK4/6 inhibitor Cyclin-dependent kinases 4 and 6 (CDK4/6) 2015-01-01
target treatment target treatment Institut Bergonié marketed CDK4/6 inhibitor CDK4/6
Palbociclib palbociclib Pfizer Inc. marketed CDK4/6 inhibitor Cyclin-dependent kinases 4 and 6 (CDK4/6)
Palbociclib in combination with AI palbociclib-in-combination-with-ai Pfizer marketed CDK inhibitor CDK4/6
Abemaciclib + Aromatase Inhibitor Abemaciclib + Aromatase Inhibitor Prof. Wolfgang Janni marketed CDK4/6 inhibitor + Aromatase inhibitor combination CDK4/6 + Aromatase
Abemaciclib + Fulvestrant Abemaciclib + Fulvestrant Prof. Wolfgang Janni marketed CDK4/6 inhibitor + estrogen receptor antagonist CDK4/6 and estrogen receptor (ER)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CDK4/6 inhibitor class)

  1. AstraZeneca · 1 drug in this class
  2. Centre Leon Berard · 1 drug in this class
  3. Draig Therapeutics Ltd · 1 drug in this class
  4. Fujian Cancer Hospital · 1 drug in this class
  5. GBG Forschungs GmbH · 1 drug in this class
  6. GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
  7. Hoffmann-La Roche · 1 drug in this class
  8. Institut Bergonié · 1 drug in this class
  9. Jiangsu Simcere Pharmaceutical Co., Ltd. · 1 drug in this class
  10. Kartos Therapeutics, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DT-101 — Competitive Intelligence Brief. https://druglandscape.com/ci/dt-101. Accessed 2026-05-13.

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