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doxorubicine + cyclophosphamide sequential — Competitive Intelligence Brief
phase 3
anthracycline antibiotic + alkylating agent
topoisomerase II
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
doxorubicine + cyclophosphamide sequential (doxorubicine + cyclophosphamide sequential) — Sanofi. Doxorubicin is a topoisomerase II inhibitor that intercalates DNA, while cyclophosphamide is an alkylating agent that cross-links DNA.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| doxorubicine + cyclophosphamide sequential TARGET | doxorubicine + cyclophosphamide sequential | Sanofi | phase 3 | anthracycline antibiotic + alkylating agent | topoisomerase II | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Idamycin Pfs | IDARUBICIN HYDROCHLORIDE | marketed | Anthracycline Topoisomerase Inhibitor | DNA, topoisomerase II | 1990-01-01 | |
| Idamycin Pfs | Idarubicin Hydrochloride | Pfizer Inc. | marketed | Anthracycline topoisomerase inhibitor | DNA, Topoisomerase II | 1990-01-01 |
| Cipro | ciprofloxacin | Bayer AG | marketed | Fluoroquinolone antibiotic | DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A | 1987-10-22 |
| Amekrin | AMSACRINE | marketed | amsacrine | DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II | 1987-01-01 | |
| DOXORUBICIN HYDROCHLORIDE | DOXORUBICIN HYDROCHLORIDE | marketed | topoisomerase II | 1974-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Cipro · 11369566 · Formulation · US
- — Cipro · 9603796 · Compound · US
- — Cipro · 9205048 · Method of Use · US
- — Cipro · 9233068 · Formulation · US
- — Cipro · 8318817 · Method of Use · US
- — Cipro · 9220796 · Formulation · US
- — Cipro · 11040004 · Method of Use · US
- — Cipro · 11246863 · Formulation · US
Sponsor landscape (anthracycline antibiotic + alkylating agent class)
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). doxorubicine + cyclophosphamide sequential — Competitive Intelligence Brief. https://druglandscape.com/ci/doxorubicine-cyclophosphamide-sequential. Accessed 2026-05-14.
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