Dorzolamide 2% drops — Competitive Intelligence Brief

Dorzolamide 2% drops (Dorzolamide 2% drops) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Carbonic anhydrase inhibitor. Area: Cardiovascular.

marketed Carbonic anhydrase inhibitor Carbonic anhydrase II Cardiovascular Small molecule

Target snapshot

Dorzolamide 2% drops (Dorzolamide 2% drops) — University Health Network, Toronto.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Dorzolamide 2% drops TARGET	Dorzolamide 2% drops	University Health Network, Toronto	marketed	Carbonic anhydrase inhibitor	Carbonic anhydrase II
Azopt	BRINZOLAMIDE	Novartis	marketed	Carbonic Anhydrase Inhibitor [EPC]	carbonic anhydrase II	1998-01-01
Cosopt PF 2%-0.5% Ophthalmic Solution	Cosopt PF 2%-0.5% Ophthalmic Solution	Prairie Eye Center	marketed	Fixed-dose combination of carbonic anhydrase inhibitor and beta-blocker	Carbonic anhydrase II (dorzolamide component); beta-adrenergic receptors (timolol component)
Xalatan+Cosopt	Xalatan+Cosopt	University of Turin, Italy	marketed	Prostaglandin analog + carbonic anhydrase inhibitor + beta-blocker combination	Prostaglandin F receptor (FP receptor); carbonic anhydrase II; beta-adrenergic receptors
Simbrinza 0.2%-1% Ophthalmic Suspension	Simbrinza 0.2%-1% Ophthalmic Suspension	Prairie Eye Center	marketed	Fixed-dose combination of carbonic anhydrase inhibitor and alpha-2 adrenergic agonist	Carbonic anhydrase II; alpha-2 adrenergic receptor
ACETAZOLAMIDE oral capsule	ACETAZOLAMIDE oral capsule	University of Zurich	marketed	Carbonic anhydrase inhibitor	Carbonic anhydrase II
Dorzolamide-timolol and latanoprost	Dorzolamide-timolol and latanoprost	Laboratorios Sophia S.A de C.V.	marketed	Fixed-dose combination of carbonic anhydrase inhibitor, beta-blocker, and prostaglandin F analog	Carbonic anhydrase II (dorzolamide), beta-1 and beta-2 adrenergic receptors (timolol), prostaglandin F receptor (latanoprost)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Carbonic anhydrase inhibitor class)

1. Bausch & Lomb Incorporated · 2 drugs in this class
2. Actavis Inc. · 2 drugs in this class
3. Beijing Tiantan Hospital · 1 drug in this class
4. Merck Sharp & Dohme LLC · 1 drug in this class
5. National University Hospital, Singapore · 1 drug in this class
6. Padagis LLC · 1 drug in this class
7. Rabin Medical Center · 1 drug in this class
8. Shahid Beheshti University of Medical Sciences · 1 drug in this class
9. Sun Pharmaceutical Industries Limited · 1 drug in this class
10. University Health Network, Toronto · 1 drug in this class