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Doravirine, Tenofovir, Lamivudine - Open-Label — Competitive Intelligence Brief

Doravirine, Tenofovir, Lamivudine - Open-Label (Doravirine, Tenofovir, Lamivudine - Open-Label) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: HIV-1 reverse transcriptase inhibitor. Area: Infectious Diseases.

phase 2 HIV-1 reverse transcriptase inhibitor HIV-1 reverse transcriptase Infectious Diseases Small molecule Live · refreshed every 30 min

Target snapshot

Doravirine, Tenofovir, Lamivudine - Open-Label (Doravirine, Tenofovir, Lamivudine - Open-Label) — Merck Sharp & Dohme LLC. Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), while Tenofovir and Lamivudine are HIV-1 nucleotide reverse transcriptase inhibitors (NtRTIs) and nucleoside reverse transcriptase inhibitors (NRTIs), respectively.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Doravirine, Tenofovir, Lamivudine - Open-Label TARGET Doravirine, Tenofovir, Lamivudine - Open-Label Merck Sharp & Dohme LLC phase 2 HIV-1 reverse transcriptase inhibitor HIV-1 reverse transcriptase
Emtricitabine and Tenofovir Emtricitabine and Tenofovir Puerto Rico Community Network for Clinical Research on AIDS marketed Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination HIV-1 reverse transcriptase
Emtricitabine / Tenofovir Disoproxil Pill Emtricitabine / Tenofovir Disoproxil Pill Fundacion IDEAA marketed Nucleoside/nucleotide reverse transcriptase inhibitor combination HIV-1 reverse transcriptase
Emtricitabine / Tenofovir Disoproxil Oral Tablet Emtricitabine / Tenofovir Disoproxil Oral Tablet University of Chicago marketed Nucleoside/nucleotide reverse transcriptase inhibitor combination HIV-1 reverse transcriptase
Etravirine (ETR) Etravirine (ETR) ViiV Healthcare marketed Non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV-1 reverse transcriptase
Doravirine (DOR) Doravirine (DOR) Walter K. Kraft marketed Non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV-1 reverse transcriptase
Emtricitabine/tenofovir disoproxil fumarate Emtricitabine/tenofovir disoproxil fumarate Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections marketed Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination HIV-1 reverse transcriptase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (HIV-1 reverse transcriptase inhibitor class)

  1. Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Doravirine, Tenofovir, Lamivudine - Open-Label — Competitive Intelligence Brief. https://druglandscape.com/ci/doravirine-tenofovir-lamivudine-open-label. Accessed 2026-05-18.

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