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Doravirine, Tenofovir, Lamivudine - Open-Label — Competitive Intelligence Brief
phase 2
HIV-1 reverse transcriptase inhibitor
HIV-1 reverse transcriptase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
Doravirine, Tenofovir, Lamivudine - Open-Label (Doravirine, Tenofovir, Lamivudine - Open-Label) — Merck Sharp & Dohme LLC. Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), while Tenofovir and Lamivudine are HIV-1 nucleotide reverse transcriptase inhibitors (NtRTIs) and nucleoside reverse transcriptase inhibitors (NRTIs), respectively.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Doravirine, Tenofovir, Lamivudine - Open-Label TARGET | Doravirine, Tenofovir, Lamivudine - Open-Label | Merck Sharp & Dohme LLC | phase 2 | HIV-1 reverse transcriptase inhibitor | HIV-1 reverse transcriptase | |
| Emtricitabine and Tenofovir | Emtricitabine and Tenofovir | Puerto Rico Community Network for Clinical Research on AIDS | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV-1 reverse transcriptase | |
| Emtricitabine / Tenofovir Disoproxil Pill | Emtricitabine / Tenofovir Disoproxil Pill | Fundacion IDEAA | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor combination | HIV-1 reverse transcriptase | |
| Emtricitabine / Tenofovir Disoproxil Oral Tablet | Emtricitabine / Tenofovir Disoproxil Oral Tablet | University of Chicago | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor combination | HIV-1 reverse transcriptase | |
| Etravirine (ETR) | Etravirine (ETR) | ViiV Healthcare | marketed | Non-nucleoside reverse transcriptase inhibitor (NNRTI) | HIV-1 reverse transcriptase | |
| Doravirine (DOR) | Doravirine (DOR) | Walter K. Kraft | marketed | Non-nucleoside reverse transcriptase inhibitor (NNRTI) | HIV-1 reverse transcriptase | |
| Emtricitabine/tenofovir disoproxil fumarate | Emtricitabine/tenofovir disoproxil fumarate | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV-1 reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HIV-1 reverse transcriptase inhibitor class)
- Merck Sharp & Dohme LLC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Doravirine, Tenofovir, Lamivudine - Open-Label — Competitive Intelligence Brief. https://druglandscape.com/ci/doravirine-tenofovir-lamivudine-open-label. Accessed 2026-05-18.
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