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Doravirine, Tenofovir, Lamivudine — Competitive Intelligence Brief
marketed
Antiretroviral combination (NNRTI + NRTIs)
HIV reverse transcriptase, HIV integrase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Doravirine, Tenofovir, Lamivudine (Doravirine, Tenofovir, Lamivudine) — Merck Sharp & Dohme LLC. This combination inhibits HIV reverse transcriptase and integrase to block viral replication and reduce viral load in HIV-infected patients.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Doravirine, Tenofovir, Lamivudine TARGET | Doravirine, Tenofovir, Lamivudine | Merck Sharp & Dohme LLC | marketed | Antiretroviral combination (NNRTI + NRTIs) | HIV reverse transcriptase, HIV integrase | |
| Atripla (r) | Atripla (r) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Antiretroviral combination (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase | |
| Atripla or Stribild | Atripla or Stribild | Fred Hutchinson Cancer Center | marketed | Antiretroviral combination therapy (NRTI/NNRTI or INSTI-based) | HIV reverse transcriptase, HIV integrase | |
| TDF/3TC/EFV or DTG or NVP | TDF/3TC/EFV or DTG or NVP | MU-JHU CARE | marketed | Antiretroviral combination therapy (NRTI + NNRTI or INSTI) | HIV reverse transcriptase, HIV integrase | |
| tenofovir, lamivudine, efavirenz | tenofovir, lamivudine, efavirenz | Bamrasnaradura Infectious Diseases Institute | marketed | Antiretroviral combination therapy (NRTI/NtRTI/NNRTI) | HIV reverse transcriptase, HIV integrase | |
| Tenofovir, lamivudine and efavirenz | Tenofovir, lamivudine and efavirenz | Centre for the AIDS Programme of Research in South Africa | marketed | Antiretroviral combination therapy (NRTI/NtRTI + NNRTI) | HIV reverse transcriptase, HIV integrase | |
| efavirenz + emtricitabina + tenofovir | efavirenz + emtricitabina + tenofovir | Hospital Universitari Vall d'Hebron Research Institute | marketed | Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination (NNRTI + NRTIs) class)
- Merck Sharp & Dohme LLC · 2 drugs in this class
- Instituto Mexicano del Seguro Social · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Doravirine, Tenofovir, Lamivudine — Competitive Intelligence Brief. https://druglandscape.com/ci/doravirine-tenofovir-lamivudine. Accessed 2026-05-17.
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