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DOR/3TC/TDF — Competitive Intelligence Brief

DOR/3TC/TDF (DOR/3TC/TDF) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiretroviral combination therapy (NNRTI + NRTI + NtRTI). Area: Infectious Disease / Virology.

marketed Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) HIV reverse transcriptase Infectious Disease / Virology Small molecule Live · refreshed every 30 min

Target snapshot

DOR/3TC/TDF (DOR/3TC/TDF) — Prism Health North Texas. DOR/3TC/TDF is a fixed-dose combination of three antiretroviral agents that work together to inhibit HIV replication through different mechanisms: reverse transcriptase inhibition and nucleotide reverse transcriptase inhibition.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DOR/3TC/TDF TARGET DOR/3TC/TDF Prism Health North Texas marketed Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) HIV reverse transcriptase
JULUCA JULUCA ViiV Healthcare marketed Antiretroviral combination (integrase inhibitor + NNRTI) HIV integrase and HIV reverse transcriptase
DOR/DTG/3TC DOR/DTG/3TC Insel Gruppe AG, University Hospital Bern marketed Antiretroviral combination (NNRTI + INSTI + NRTI) HIV reverse transcriptase, HIV integrase
First-line Antiretroviral Therapy First-line Antiretroviral Therapy UPECLIN HC FM Botucatu Unesp marketed Antiretroviral combination therapy (NRTI/NNRTI/PI/INSTI) HIV reverse transcriptase, HIV protease, HIV integrase (depending on regimen components)
Antiretroviral/Anti HIV Antiretroviral/Anti HIV MSD Pharmaceuticals LLC marketed Antiretroviral agent (multiple classes: NRTI, NNRTI, PI, INSTI, entry inhibitor) HIV reverse transcriptase, HIV protease, HIV integrase, CCR5, or CXCR4 (depending on specific agent)
Darunavir, Ritonavir, Truvada Darunavir, Ritonavir, Truvada Imperial College London marketed Antiretroviral combination therapy (protease inhibitor + reverse transcriptase inhibitors) HIV protease, HIV reverse transcriptase, CYP3A4
Antiretroviral therapy plus Interleukin-2 Antiretroviral therapy plus Interleukin-2 Juan A. Arnaiz marketed Combination immunotherapy and antiviral HIV reverse transcriptase, protease, integrase (ART component); IL-2 receptor (IL-2 component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) class)

  1. Hospital Universitari Vall d'Hebron Research Institute · 1 drug in this class
  2. Prism Health North Texas · 1 drug in this class
  3. St Stephens Aids Trust · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DOR/3TC/TDF — Competitive Intelligence Brief. https://druglandscape.com/ci/dor-3tc-tdf. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing