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DOR/3TC/TDF — Competitive Intelligence Brief
marketed
Antiretroviral combination therapy (NNRTI + NRTI + NtRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
DOR/3TC/TDF (DOR/3TC/TDF) — Prism Health North Texas. DOR/3TC/TDF is a fixed-dose combination of three antiretroviral agents that work together to inhibit HIV replication through different mechanisms: reverse transcriptase inhibition and nucleotide reverse transcriptase inhibition.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DOR/3TC/TDF TARGET | DOR/3TC/TDF | Prism Health North Texas | marketed | Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase | |
| JULUCA | JULUCA | ViiV Healthcare | marketed | Antiretroviral combination (integrase inhibitor + NNRTI) | HIV integrase and HIV reverse transcriptase | |
| DOR/DTG/3TC | DOR/DTG/3TC | Insel Gruppe AG, University Hospital Bern | marketed | Antiretroviral combination (NNRTI + INSTI + NRTI) | HIV reverse transcriptase, HIV integrase | |
| First-line Antiretroviral Therapy | First-line Antiretroviral Therapy | UPECLIN HC FM Botucatu Unesp | marketed | Antiretroviral combination therapy (NRTI/NNRTI/PI/INSTI) | HIV reverse transcriptase, HIV protease, HIV integrase (depending on regimen components) | |
| Antiretroviral/Anti HIV | Antiretroviral/Anti HIV | MSD Pharmaceuticals LLC | marketed | Antiretroviral agent (multiple classes: NRTI, NNRTI, PI, INSTI, entry inhibitor) | HIV reverse transcriptase, HIV protease, HIV integrase, CCR5, or CXCR4 (depending on specific agent) | |
| Darunavir, Ritonavir, Truvada | Darunavir, Ritonavir, Truvada | Imperial College London | marketed | Antiretroviral combination therapy (protease inhibitor + reverse transcriptase inhibitors) | HIV protease, HIV reverse transcriptase, CYP3A4 | |
| Antiretroviral therapy plus Interleukin-2 | Antiretroviral therapy plus Interleukin-2 | Juan A. Arnaiz | marketed | Combination immunotherapy and antiviral | HIV reverse transcriptase, protease, integrase (ART component); IL-2 receptor (IL-2 component) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) class)
- Hospital Universitari Vall d'Hebron Research Institute · 1 drug in this class
- Prism Health North Texas · 1 drug in this class
- St Stephens Aids Trust · 1 drug in this class
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Cite this brief
Drug Landscape (2026). DOR/3TC/TDF — Competitive Intelligence Brief. https://druglandscape.com/ci/dor-3tc-tdf. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing