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docetaxel - cisplatin - 5-fluorouracil — Competitive Intelligence Brief
phase 3
Taxane and platinum-based chemotherapy
Microtubules and DNA
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
docetaxel - cisplatin - 5-fluorouracil (docetaxel - cisplatin - 5-fluorouracil) — Gruppo Oncologico del Nord-Ovest. Docetaxel inhibits microtubule dynamics, disrupting cell division, while cisplatin induces DNA crosslinks, and 5-fluorouracil inhibits thymidylate synthase.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| docetaxel - cisplatin - 5-fluorouracil TARGET | docetaxel - cisplatin - 5-fluorouracil | Gruppo Oncologico del Nord-Ovest | phase 3 | Taxane and platinum-based chemotherapy | Microtubules and DNA | |
| Taxanes plus Carboplatin | Taxanes plus Carboplatin | Shanghai Jiao Tong University School of Medicine | phase 3 | Taxane and platinum-based chemotherapeutic agent | Microtubules and DNA | |
| Vincristin , Adriamycin, Dexamethasone = VAD | Vincristin , Adriamycin, Dexamethasone = VAD | University Hospital, Caen | phase 3 | Vinca alkaloid and anthracycline antibiotic | Microtubules and DNA | |
| paclitaxel plus carboplatin | paclitaxel plus carboplatin | Immatics US, Inc. | phase 3 | Taxane and platinum-based chemotherapy | ||
| docetaxel and carboplatin | docetaxel and carboplatin | Sanofi | phase 3 | Taxane and platinum-based chemotherapy |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Taxane and platinum-based chemotherapy class)
- Gruppo Oncologico del Nord-Ovest · 1 drug in this class
- Immatics US, Inc. · 1 drug in this class
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). docetaxel - cisplatin - 5-fluorouracil — Competitive Intelligence Brief. https://druglandscape.com/ci/docetaxel-cisplatin-5-fluorouracil. Accessed 2026-05-17.
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