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Divalproex (DV) — Competitive Intelligence Brief
marketed
Histone deacetylase inhibitor; anticonvulsant; mood stabilizer
Histone deacetylase; GABA metabolism; sodium and calcium channels
Neurology; Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Divalproex (DV) (Divalproex (DV)) — Weill Medical College of Cornell University. Divalproex inhibits histone deacetylase and enhances GABA neurotransmission, leading to increased inhibitory signaling in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Divalproex (DV) TARGET | Divalproex (DV) | Weill Medical College of Cornell University | marketed | Histone deacetylase inhibitor; anticonvulsant; mood stabilizer | Histone deacetylase; GABA metabolism; sodium and calcium channels | |
| Duvyzat | GIVINOSTAT | Italfarmaco Spa | marketed | Histone Deacetylase Inhibitor [EPC] | 2024-01-01 | |
| Farydak | PANOBINOSTAT | Secura | marketed | Histone Deacetylase Inhibitor | Histone deacetylase 4 | 2015-01-01 |
| Beleodaq | belinostat | Acrotech Biopharma | marketed | Histone Deacetylase Inhibitor [EPC] | Histone deacetylase 1 | 2014-01-01 |
| BELINOSTAT | BELINOSTAT | marketed | Histone Deacetylase Inhibitor [EPC] | 2014-01-01 | ||
| Istodax | ROMIDEPSIN | Teva Pharms Usa Inc | marketed | Histone Deacetylase Inhibitor | HDACs | 2009-01-01 |
| Zolinza | VORINOSTAT | Merck & Co. | marketed | Histone Deacetylase Inhibitor [EPC] | Histone deacetylase 6 | 2006-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Histone deacetylase inhibitor; anticonvulsant; mood stabilizer class)
- National Institute on Drug Abuse (NIDA) · 1 drug in this class
- Sanofi · 1 drug in this class
- Weill Medical College of Cornell University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Divalproex (DV) — Competitive Intelligence Brief. https://druglandscape.com/ci/divalproex-dv. Accessed 2026-05-13.
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