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Last reviewed 2026-06-10 · How we verify

Thrombotic thrombocytopenic purpura — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Thrombotic thrombocytopenic purpura (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Thrombotic thrombocytopenic purpura, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Calibvi	CAPLACIZUMAB	Ablynx Nv		von Willebrand factor	2019-01-01
Mabthera	rituxan	Roche	CD20-directed Cytolytic Antibody	B-lymphocyte antigen CD20	1997-01-01
Mabthera	Rituximab-Pvvr	Roche	Monoclonal antibody	CD20 antigen on pre-B and mature B-lymphocytes	1997-01-01
Mabthera	rituximab	Roche	CD20-directed Cytolytic Antibody [EPC]	B-lymphocyte antigen CD20	1997-01-01
CABLIVI	CAPLACIZUMAB-YHDP	ABLYNX NV		von Willebrand factor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Roche · 3 drugs in Thrombotic thrombocytopenic purpura
ABLYNX NV · 1 drug in Thrombotic thrombocytopenic purpura
Ablynx Nv · 1 drug in Thrombotic thrombocytopenic purpura

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Every new regulatory action, PDUFA date, or trial completion in Thrombotic thrombocytopenic purpura:

Cite this brief

Drug Landscape (2026). Thrombotic thrombocytopenic purpura — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/thrombotic-thrombocytopenic-purpura. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing