How many drugs treat Systemic sclerosis?

Drug Landscape tracks 5 marketed treatments for Systemic sclerosis (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

Systemic sclerosis — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Systemic sclerosis (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Systemic sclerosis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Tracleer	BOSENTAN	AstraZeneca	Endothelin Receptor Antagonist	Endothelin-1 receptor	2001-01-01
Mabthera	rituxan	Roche	CD20-directed Cytolytic Antibody	B-lymphocyte antigen CD20	1997-01-01
Mabthera	Rituximab-Pvvr	Roche	Monoclonal antibody	CD20 antigen on pre-B and mature B-lymphocytes	1997-01-01
Mabthera	rituximab	Roche	CD20-directed Cytolytic Antibody [EPC]	B-lymphocyte antigen CD20	1997-01-01
tocilizumab or sarilumab	tocilizumab-or-sarilumab	Pfizer	monoclonal antibody	interleukin-6 receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

· 3 drugs in Systemic sclerosis
Roche · 3 drugs in Systemic sclerosis
AstraZeneca · 1 drug in Systemic sclerosis
Pfizer · 1 drug in Systemic sclerosis

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Every new regulatory action, PDUFA date, or trial completion in Systemic sclerosis:

Cite this brief

Drug Landscape (2026). Systemic sclerosis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/systemic-sclerosis. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing