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Rheumatic heart disease — Treatment Landscape & Competitive Intelligence

Rheumatic heart disease (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Rheumatic heart disease, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Decadron dexamethasone Generic (originally Merck) Corticosteroid [EPC] Annexin A1, Interleukin-4, Androgen receptor 1958-10-30
Medrol methylprednisolone Generic (originally Upjohn/Pfizer) Glucocorticoid (corticosteroid) Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor 1957-10-01
Prelone prednisolone Generic (originally Schering) Glucocorticoid (corticosteroid) Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1 1955-01-01
Deltasone prednisone Generic (originally Schering) Corticosteroid [EPC] Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor 1955-01-01
Solu-Cortef hydrocortisone succinate Pfizer Corticosteroid Glucocorticoid receptor 1955-01-01
Cortef hydrocortisone Generic (originally Merck/Upjohn) Corticosteroid [EPC] Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible 1952-01-01
Cortifoam HYDROCORTISONE ACETATE Pfizer Corticosteroid Corticosteroid-binding globulin 1951-01-01
prednison prednison Wen Zhang Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor
Cortisol Cortisol University of Zurich Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible
prednisolon prednisolon Hannover Medical School Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 4 drugs in Rheumatic heart disease
  2. Pfizer · 2 drugs in Rheumatic heart disease
  3. Generic (originally Schering) · 2 drugs in Rheumatic heart disease
  4. Generic (originally Upjohn/Pfizer) · 1 drug in Rheumatic heart disease
  5. Hannover Medical School · 1 drug in Rheumatic heart disease
  6. Leiden University Medical Center · 1 drug in Rheumatic heart disease
  7. University of Zurich · 1 drug in Rheumatic heart disease
  8. Wen Zhang · 1 drug in Rheumatic heart disease
  9. Generic (originally Merck) · 1 drug in Rheumatic heart disease
  10. Generic (originally Merck/Upjohn) · 1 drug in Rheumatic heart disease

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Every new regulatory action, PDUFA date, or trial completion in Rheumatic heart disease:

Cite this brief

Drug Landscape (2026). Rheumatic heart disease — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/rheumatic-heart-disease. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing