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Last reviewed 2026-06-10 · How we verify

Primary progressive multiple sclerosis — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Primary progressive multiple sclerosis (disease) competitive landscape: 2 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

2 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Primary progressive multiple sclerosis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Ocrevus	OCRELIZUMAB	Roche	CD20-directed Cytolytic Antibody [EPC]	B-lymphocyte antigen CD20		2017-01-01
Ocrevus	Ocrevus	Kessler Foundation		B-lymphocyte antigen CD20

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Kessler Foundation · 1 drug in Primary progressive multiple sclerosis
Roche · 1 drug in Primary progressive multiple sclerosis

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Cite this brief

Drug Landscape (2026). Primary progressive multiple sclerosis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/primary-progressive-multiple-sclerosis. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing