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Last reviewed 2026-06-10 · How we verify

Primary hemophagocytic lymphohistiocytosis — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Primary hemophagocytic lymphohistiocytosis (disease) competitive landscape: 2 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

2 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Primary hemophagocytic lymphohistiocytosis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Gamifant	EMAPALUMAB	Novimmune S.A.	Interferon gamma Blocker [EPC]	Interferon gamma		2018-01-01
Emapalumab-Lzsg	Emapalumab-Lzsg	Swedish Orphan Biovitrum	Interferon gamma Blocker [EPC]	Interferon gamma

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Novimmune S.A. · 1 drug in Primary hemophagocytic lymphohistiocytosis
Swedish Orphan Biovitrum · 1 drug in Primary hemophagocytic lymphohistiocytosis

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Cite this brief

Drug Landscape (2026). Primary hemophagocytic lymphohistiocytosis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/primary-hemophagocytic-lymphohistiocytosis. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing