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Last reviewed 2026-06-10 · How we verify

polyneuropathy of hereditary transthyretin-mediated amyloidosis — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

polyneuropathy of hereditary transthyretin-mediated amyloidosis (disease) competitive landscape: 1 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

1 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating polyneuropathy of hereditary transthyretin-mediated amyloidosis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Wainua	EPLONTERSEN	Astrazeneca Ab	Transthyretin-directed RNA Interaction [EPC]			2025-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Astrazeneca Ab · 1 drug in polyneuropathy of hereditary transthyretin-mediated amyloidosis

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Every new regulatory action, PDUFA date, or trial completion in polyneuropathy of hereditary transthyretin-mediated amyloidosis:

Cite this brief

Drug Landscape (2026). polyneuropathy of hereditary transthyretin-mediated amyloidosis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/polyneuropathy-of-hereditary-transthyretin-mediated-amyloidosis. Accessed 2026-06-10.

polyneuropathy of hereditary transthyretin-mediated amyloidosis full disease profile — treatment pathway, diagnostics, guidelines
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing