How many drugs treat Opioid withdrawal?

Drug Landscape tracks 3 marketed treatments for Opioid withdrawal (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Subscribe to /feed/disease/opioid-withdrawal.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Opioid withdrawal — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Opioid withdrawal (disease) competitive landscape: 3 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

3 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Opioid withdrawal, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Lucemyra	LOFEXIDINE	Biocorrx Pharms	lofexidine	Alpha-2A adrenergic receptor	2018-01-01
Methadone Hydrochloride	METHADONE	Specgx Llc	Opioid Agonist	mu-opioid receptors, NMDA receptor	1947-01-01
Methadon	Methadon	University of Utah		Neuronal acetylcholine receptor subunit alpha-10, D(4) dopamine receptor, D(3) dopamine receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Biocorrx Pharms · 1 drug in Opioid withdrawal
Specgx Llc · 1 drug in Opioid withdrawal
University of Utah · 1 drug in Opioid withdrawal

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Every new regulatory action, PDUFA date, or trial completion in Opioid withdrawal:

Cite this brief

Drug Landscape (2026). Opioid withdrawal — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/opioid-withdrawal. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing