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Non-small cell lung cancer — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| PF-06939999 in combination with docetaxel | pf-06939999-in-combination-with-docetaxel | Pfizer | Small molecule inhibitor | Specific protein kinase | Not yet determined | |
| Gavreto | PRALSETINIB | Rigel Pharms | Kinase Inhibitor [EPC] | RET | 2020-01-01 | |
| Lorbrena | lorlatinib | Pfizer | Kinase Inhibitor [EPC] | ALK tyrosine kinase receptor | 2018-01-01 | |
| Imfinzi | durvalumab | AstraZeneca | Programmed Death Ligand-1 Blocker [EPC] | Programmed cell death 1 ligand 1 | 2017-01-01 | |
| Alunbrig | brigatinib | Takeda | Kinase Inhibitor [EPC] | ALK tyrosine kinase receptor | 2017-01-01 | |
| Alecensa | alectinib | Hoffmann-La Roche | Kinase Inhibitor | ALK tyrosine kinase receptor | 2015-01-01 | |
| Portrazza | NECITUMUMAB | Eli Lilly Co | Epidermal Growth Factor Receptor Antagonist [EPC] | Epidermal growth factor receptor | 2015-01-01 | |
| Zykadia | ceritinib | Novartis | Kinase Inhibitor [EPC] | ALK tyrosine kinase receptor | 2014-01-01 | |
| Ofev | NINTEDANIB | Boehringer Ingelheim | Kinase Inhibitor | Receptor-type tyrosine-protein kinase FLT3 | 2014-01-01 | |
| Cyramza | RAMUCIRUMAB | Eli Lilly | Vascular Endothelial Growth Factor Receptor 2 Antagonist [EPC] | Vascular endothelial growth factor receptor 2 | 2014-01-01 |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
- — Ofev · FDA · approved · US
- — Ofev · FDA · approved · US
- — Ofev · FDA · approved · US
- — Ofev · FDA · approved · US
- — Ofev · MOH · likely_approved · IL
- — Ofev · HSA · likely_approved · SG
- — Ofev · SFDA · likely_approved · SA
- — Ofev · MOH · likely_approved · AE
- — Ofev · MFDS · likely_approved · KR
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Pfizer · 13 drugs in Non-small cell lung cancer
- M.D. Anderson Cancer Center · 2 drugs in Non-small cell lung cancer
- Accord Hlthcare · 2 drugs in Non-small cell lung cancer
- Pfizer Inc. · 2 drugs in Non-small cell lung cancer
- Boehringer Ingelheim · 2 drugs in Non-small cell lung cancer
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences · 1 drug in Non-small cell lung cancer
- Bristol-Myers Squibb · 1 drug in Non-small cell lung cancer
- Actavis · 1 drug in Non-small cell lung cancer
- Eli Lilly · 1 drug in Non-small cell lung cancer
- David Adelstein · 1 drug in Non-small cell lung cancer
- Eli Lilly Co · 1 drug in Non-small cell lung cancer
- Concordia Labs Inc · 1 drug in Non-small cell lung cancer
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Cite this brief
Drug Landscape (2026). Non-small cell lung cancer — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/non-small-cell-lung-cancer. Accessed 2026-05-16.
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