Last reviewed · How we verify

Neuromyelitis optica — Treatment Landscape & Competitive Intelligence

Neuromyelitis optica (disease) competitive landscape: 7 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

7 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Neuromyelitis optica, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Uplizna INEBILIZUMAB Viela Bio CD19-directed Cytolytic Antibody [EPC] B-lymphocyte antigen CD19 2020-01-01
H5G1.1 ECULIZUMAB AstraZeneca Complement Inhibitor [EPC] C5 2007-01-01
Mabthera rituxan Roche CD20-directed Cytolytic Antibody B-lymphocyte antigen CD20 1997-01-01
Mabthera Rituximab-Pvvr Roche Monoclonal antibody CD20 antigen on pre-B and mature B-lymphocytes 1997-01-01
Mabthera rituximab Roche CD20-directed Cytolytic Antibody [EPC] B-lymphocyte antigen CD20 1997-01-01
UPLIZNA INEBILIZUMAB-CDON VIELA BIO CD19-directed Cytolytic Antibody [EPC] Low affinity immunoglobulin gamma Fc region receptor III-A, B-lymphocyte antigen CD19
Soliris Soliris Apellis Pharmaceuticals, Inc. Complement C5

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Roche · 3 drugs in Neuromyelitis optica
  2. Apellis Pharmaceuticals, Inc. · 1 drug in Neuromyelitis optica
  3. AstraZeneca · 1 drug in Neuromyelitis optica
  4. VIELA BIO · 1 drug in Neuromyelitis optica
  5. Viela Bio · 1 drug in Neuromyelitis optica

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Neuromyelitis optica:

Cite this brief

Drug Landscape (2026). Neuromyelitis optica — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/neuromyelitis-optica. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing