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moderate-to-severe atopic dermatitis — Treatment Landscape & Competitive Intelligence

moderate-to-severe atopic dermatitis (disease) competitive landscape: 8 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

8 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating moderate-to-severe atopic dermatitis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Ebglyss LEBRIKIZUMAB Eli Lilly And Co Interleukin-13 Antagonist [EPC] 2025-01-01
Adbry TRALOKINUMAB Leo Pharma As Interleukin-13 Antagonist [EPC] Interleukin-13 2021-01-01
Abrocitinib Suspension F2 abrocitinib-suspension-f2 Pfizer unknown unknown
Induction- PF-06480605 450 mg SC Q4W induction-pf-06480605-450-mg-sc-q4w Pfizer small molecule IL-17 receptor
Chronic- PF-06480605 150 mg SC Q4W chronic-pf-06480605-150-mg-sc-q4w Pfizer Janus kinase inhibitor JAK1 and JAK2 enzymes
Chronic- PF-06480605 450 mg SC Q4W chronic-pf-06480605-450-mg-sc-q4w Pfizer pharmacological class not specified IL-4 receptor alpha subunit
Chronic- PF-06480605 50 mg SC Q4W chronic-pf-06480605-50-mg-sc-q4w Pfizer JAK inhibitor JAK pathway
Induction- PF-06480605 150 mg SC Q4W induction-pf-06480605-150-mg-sc-q4w Pfizer JAK inhibitor JAK pathway

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Pfizer · 6 drugs in moderate-to-severe atopic dermatitis
  2. Eli Lilly And Co · 1 drug in moderate-to-severe atopic dermatitis
  3. Leo Pharma As · 1 drug in moderate-to-severe atopic dermatitis

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Every new regulatory action, PDUFA date, or trial completion in moderate-to-severe atopic dermatitis:

Cite this brief

Drug Landscape (2026). moderate-to-severe atopic dermatitis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/moderate-to-severe-atopic-dermatitis. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing