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Mixed bipolar I disorder — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Vraylar | CARIPRAZINE | AbbVie | Atypical Antipsychotic [EPC] | D(3) dopamine receptor | 2015-01-01 | |
| Saphris | ASENAPINE | Hisamitsu | Atypical Antipsychotic [EPC] | 5-hydroxytryptamine receptor 2C | 2009-01-01 | |
| Abilify | aripiprazole | Generic (originally Otsuka/BMS) | Third-generation antipsychotic (D2 partial agonist) | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | 2002-11-15 | |
| Geodon | ziprasidone | Pfizer Inc. | Atypical antipsychotic (second-generation) | Aspartate aminotransferase, cytoplasmic, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A | 2001-02-05 | |
| Risperdal | risperidone | Johnson & Johnson (Janssen) | Atypical Antipsychotic [EPC] | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 | 1993-12-29 | |
| Tegretol | carbamazepine | Novartis AG (originally Geigy) | Mood Stabilizer [EPC] | Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4 | 1968-03-11 | |
| Zyprexa | Zyprexa | Washington University School of Medicine | Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A | |||
| Zyprexa | olanzapine | Eli Lilly | Atypical Antipsychotic [EPC] | Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A | ||
| Carbamazepin | Carbamazepin | Enanta Pharmaceuticals, Inc | Frizzled-8, Nuclear receptor subfamily 1 group I member 2, Neuronal acetylcholine receptor; alpha2/beta4 | |||
| Risperdal | Risperdal | Ohio State University | 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- AbbVie · 1 drug in Mixed bipolar I disorder
- Eli Lilly · 1 drug in Mixed bipolar I disorder
- Enanta Pharmaceuticals, Inc · 1 drug in Mixed bipolar I disorder
- Generic (originally Otsuka/BMS) · 1 drug in Mixed bipolar I disorder
- Hisamitsu · 1 drug in Mixed bipolar I disorder
- Johnson & Johnson (Janssen) · 1 drug in Mixed bipolar I disorder
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in Mixed bipolar I disorder
- Novartis AG (originally Geigy) · 1 drug in Mixed bipolar I disorder
- Ohio State University · 1 drug in Mixed bipolar I disorder
- Pfizer Inc. · 1 drug in Mixed bipolar I disorder
- Washington University School of Medicine · 1 drug in Mixed bipolar I disorder
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Cite this brief
Drug Landscape (2026). Mixed bipolar I disorder — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/mixed-bipolar-i-disorder. Accessed 2026-06-10.
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