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Mantle cell lymphoma — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Brukinsa | BGB-3111 | Beigene Usa Inc | Kinase Inhibitor [EPC] | Tyrosine-protein kinase BTK | 2019-01-01 | |
| Calquence | ACALABRUTINIB | AstraZeneca | Kinase Inhibitor [EPC] | Tyrosine-protein kinase BTK | 2017-01-01 | |
| Imbruvica | ibrutinib | AbbVie | Kinase Inhibitor [EPC] | Tyrosine-protein kinase Blk | 2013-01-01 | |
| Torisel | temsirolimus | Pfizer | Kinase Inhibitor | Serine/threonine-protein kinase mTOR | 2007-01-01 | |
| Revlimid | lenalidomide | Bristol-Myers Squibb | Thalidomide analogue | Cereblon (component of cullin ring E3 ubiquitin ligase enzyme complex) | 2005-01-01 | |
| Velcade | bortezomib | Shilpa | Proteasome inhibitor | 26S proteasome chymotrypsin-like activity | 2003-01-01 | |
| Fludara | FLUDARABINE PHOSPHATE | Nihon Schering K.K. | Nucleoside Metabolic Inhibitor | Carbonic anhydrase 5A, mitochondrial | 1991-01-01 | |
| Revlimid | Revlimid | M.D. Anderson Cancer Center | Bromodomain-containing protein 4, Protein cereblon, Tumor necrosis factor | |||
| Velcade | Velcade | University of Arkansas | 26S proteasome non-ATPase regulatory subunit 1, PH and SEC7 domain-containing protein 1, Cathepsin G | |||
| Imbruvica | Imbruvica | Rabin Medical Center | Nuclear receptor subfamily 4 group A member 3, Platelet glycoprotein VI, Serine/threonine-protein kinase LATS1 |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- AbbVie · 1 drug in Mantle cell lymphoma
- AstraZeneca · 1 drug in Mantle cell lymphoma
- Azienda Ospedaliera San Giovanni Battista · 1 drug in Mantle cell lymphoma
- Beigene Usa Inc · 1 drug in Mantle cell lymphoma
- Bristol-Myers Squibb · 1 drug in Mantle cell lymphoma
- Celyad Oncology SA · 1 drug in Mantle cell lymphoma
- M.D. Anderson Cancer Center · 1 drug in Mantle cell lymphoma
- Nihon Schering K.K. · 1 drug in Mantle cell lymphoma
- Pfizer · 1 drug in Mantle cell lymphoma
- Rabin Medical Center · 1 drug in Mantle cell lymphoma
- Shilpa · 1 drug in Mantle cell lymphoma
- Singapore General Hospital · 1 drug in Mantle cell lymphoma
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Cite this brief
Drug Landscape (2026). Mantle cell lymphoma — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/mantle-cell-lymphoma. Accessed 2026-06-10.
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