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Mantle cell lymphoma — Treatment Landscape & Competitive Intelligence

Mantle cell lymphoma (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Mantle cell lymphoma, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Brukinsa BGB-3111 Beigene Usa Inc Kinase Inhibitor [EPC] Tyrosine-protein kinase BTK 2019-01-01
Calquence ACALABRUTINIB AstraZeneca Kinase Inhibitor [EPC] Tyrosine-protein kinase BTK 2017-01-01
Imbruvica ibrutinib AbbVie Kinase Inhibitor [EPC] Tyrosine-protein kinase Blk 2013-01-01
Torisel temsirolimus Pfizer Kinase Inhibitor Serine/threonine-protein kinase mTOR 2007-01-01
Revlimid lenalidomide Bristol-Myers Squibb Thalidomide analogue Cereblon (component of cullin ring E3 ubiquitin ligase enzyme complex) 2005-01-01
Velcade bortezomib Shilpa Proteasome inhibitor 26S proteasome chymotrypsin-like activity 2003-01-01
Fludara FLUDARABINE PHOSPHATE Nihon Schering K.K. Nucleoside Metabolic Inhibitor Carbonic anhydrase 5A, mitochondrial 1991-01-01
Revlimid Revlimid M.D. Anderson Cancer Center Bromodomain-containing protein 4, Protein cereblon, Tumor necrosis factor
Velcade Velcade University of Arkansas 26S proteasome non-ATPase regulatory subunit 1, PH and SEC7 domain-containing protein 1, Cathepsin G
Imbruvica Imbruvica Rabin Medical Center Nuclear receptor subfamily 4 group A member 3, Platelet glycoprotein VI, Serine/threonine-protein kinase LATS1

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. AbbVie · 1 drug in Mantle cell lymphoma
  2. AstraZeneca · 1 drug in Mantle cell lymphoma
  3. Azienda Ospedaliera San Giovanni Battista · 1 drug in Mantle cell lymphoma
  4. Beigene Usa Inc · 1 drug in Mantle cell lymphoma
  5. Bristol-Myers Squibb · 1 drug in Mantle cell lymphoma
  6. Celyad Oncology SA · 1 drug in Mantle cell lymphoma
  7. M.D. Anderson Cancer Center · 1 drug in Mantle cell lymphoma
  8. Nihon Schering K.K. · 1 drug in Mantle cell lymphoma
  9. Pfizer · 1 drug in Mantle cell lymphoma
  10. Rabin Medical Center · 1 drug in Mantle cell lymphoma
  11. Shilpa · 1 drug in Mantle cell lymphoma
  12. Singapore General Hospital · 1 drug in Mantle cell lymphoma

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Every new regulatory action, PDUFA date, or trial completion in Mantle cell lymphoma:

Cite this brief

Drug Landscape (2026). Mantle cell lymphoma — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/mantle-cell-lymphoma. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing