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Hereditary angioneurotic edema — Treatment Landscape & Competitive Intelligence
6 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Orladeyo | BEROTRALSTAT | Biocryst | Plasma Kallikrein Inhibitor | Plasma kallikrein | 2020-01-01 | |
| Takhzyro | LANADELUMAB | Dyax Corp | Plasma Kallikrein Inhibitor [EPC] | plasma kallikrein | 2018-01-01 | |
| Firazyr | ICATIBANT | Takeda | Bradykinin B2 Receptor Antagonist | B2 bradykinin receptor | 2011-01-01 | |
| Kalbitor | ECALLANTIDE | Dyax Corp. | Plasma Kallikrein Inhibitor [EPC] | Plasma kallikrein | 2009-01-01 | |
| Firazyr | Firazyr | Sebastian Videla | B1 bradykinin receptor, B2 bradykinin receptor, B1 bradykinin receptor | |||
| TAKHZYRO | LANADELUMAB-FLYO | DYAX CORP. | Plasma Kallikrein Inhibitor [EPC] | Plasma kallikrein |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- · 1 drug in Hereditary angioneurotic edema
- Biocryst · 1 drug in Hereditary angioneurotic edema
- DYAX CORP. · 1 drug in Hereditary angioneurotic edema
- Dyax Corp · 1 drug in Hereditary angioneurotic edema
- Dyax Corp. · 1 drug in Hereditary angioneurotic edema
- Sebastian Videla · 1 drug in Hereditary angioneurotic edema
- Takeda · 1 drug in Hereditary angioneurotic edema
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Cite this brief
Drug Landscape (2026). Hereditary angioneurotic edema — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/hereditary-angioneurotic-edema. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing