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Hereditary angioneurotic edema — Treatment Landscape & Competitive Intelligence

Hereditary angioneurotic edema (disease) competitive landscape: 6 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

6 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Hereditary angioneurotic edema, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Orladeyo BEROTRALSTAT Biocryst Plasma Kallikrein Inhibitor Plasma kallikrein 2020-01-01
Takhzyro LANADELUMAB Dyax Corp Plasma Kallikrein Inhibitor [EPC] plasma kallikrein 2018-01-01
Firazyr ICATIBANT Takeda Bradykinin B2 Receptor Antagonist B2 bradykinin receptor 2011-01-01
Kalbitor ECALLANTIDE Dyax Corp. Plasma Kallikrein Inhibitor [EPC] Plasma kallikrein 2009-01-01
Firazyr Firazyr Sebastian Videla B1 bradykinin receptor, B2 bradykinin receptor, B1 bradykinin receptor
TAKHZYRO LANADELUMAB-FLYO DYAX CORP. Plasma Kallikrein Inhibitor [EPC] Plasma kallikrein

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 1 drug in Hereditary angioneurotic edema
  2. Biocryst · 1 drug in Hereditary angioneurotic edema
  3. DYAX CORP. · 1 drug in Hereditary angioneurotic edema
  4. Dyax Corp · 1 drug in Hereditary angioneurotic edema
  5. Dyax Corp. · 1 drug in Hereditary angioneurotic edema
  6. Sebastian Videla · 1 drug in Hereditary angioneurotic edema
  7. Takeda · 1 drug in Hereditary angioneurotic edema

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Every new regulatory action, PDUFA date, or trial completion in Hereditary angioneurotic edema:

Cite this brief

Drug Landscape (2026). Hereditary angioneurotic edema — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/hereditary-angioneurotic-edema. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing