How many drugs treat HER2-negative breast cancer?

Drug Landscape tracks 1 marketed treatments for HER2-negative breast cancer (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

How do I subscribe to ongoing alerts?

Subscribe to /feed/disease/her2-negative-breast-cancer.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

HER2-negative breast cancer — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

HER2-negative breast cancer (disease) competitive landscape: 1 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

1 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating HER2-negative breast cancer, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Pembrolizuma	Pembrolizuma	Memorial Sloan Kettering Cancer Center		Programmed cell death protein 1

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Memorial Sloan Kettering Cancer Center · 1 drug in HER2-negative breast cancer

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in HER2-negative breast cancer:

Cite this brief

Drug Landscape (2026). HER2-negative breast cancer — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/her2-negative-breast-cancer. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing