How many drugs treat Hepatic encephalopathy?

Drug Landscape tracks 5 marketed treatments for Hepatic encephalopathy (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

What's the most recent regulatory action in Hepatic encephalopathy?

Most recent: xifaxan — FDA approved.

How do I subscribe to ongoing alerts?

Subscribe to /feed/disease/hepatic-encephalopathy.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Hepatic encephalopathy — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hepatic encephalopathy (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Hepatic encephalopathy, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Cephulac	LACTULOSE	Sanwa Kagaku Kenkyusho Co., Ltd.	Osmotic Laxative [EPC]		1976-01-01
Cortisporin	NEOMYCIN	Pfizer	Aminoglycoside Antibacterial	Transient receptor potential cation channel subfamily V member 1	1957-01-01
Xifaxan	rifaximin	Bausch Health	Rifamycin Antibacterial [EPC]	Nuclear receptor subfamily 1 group I member 2, Bacterial DNA-directed RNA polymerase
Rifaximine	Rifaximine	Ain Shams University		Nuclear receptor subfamily 1 group I member 2, Bacterial DNA-directed RNA polymerase
xifaxan	xifaxan	Children's Hospital Los Angeles		Nuclear receptor subfamily 1 group I member 2, Bacterial DNA-directed RNA polymerase

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

2026-03-19 — xifaxan · FDA · approved · US

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Ain Shams University · 1 drug in Hepatic encephalopathy
Bausch Health · 1 drug in Hepatic encephalopathy
Children's Hospital Los Angeles · 1 drug in Hepatic encephalopathy
Pfizer · 1 drug in Hepatic encephalopathy
Sanwa Kagaku Kenkyusho Co., Ltd. · 1 drug in Hepatic encephalopathy

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Hepatic encephalopathy:

Cite this brief

Drug Landscape (2026). Hepatic encephalopathy — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/hepatic-encephalopathy. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing