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Last reviewed 2026-06-10 · How we verify

Hemoglobin SS disease with crisis — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hemoglobin SS disease with crisis (disease) competitive landscape: 4 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

4 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Hemoglobin SS disease with crisis, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Target
Siklos	Siklos	Theravia	Carbonic anhydrase 2, Carbonic anhydrase 5A, mitochondrial, Carbonic anhydrase 9
Xromi	Xromi	Nova Laboratories Limited	Carbonic anhydrase 2, Carbonic anhydrase 5A, mitochondrial, Carbonic anhydrase 9
Hydroxycarbamide	Hydroxycarbamide	University of Birmingham	Carbonic anhydrase 2, Carbonic anhydrase 5A, mitochondrial, Carbonic anhydrase 9
Hydroxycarbamid	Hydroxycarbamid	Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts	Carbonic anhydrase 2, Carbonic anhydrase 5A, mitochondrial, Carbonic anhydrase 9

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts · 1 drug in Hemoglobin SS disease with crisis
Nova Laboratories Limited · 1 drug in Hemoglobin SS disease with crisis
Theravia · 1 drug in Hemoglobin SS disease with crisis
University of Birmingham · 1 drug in Hemoglobin SS disease with crisis

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Cite this brief

Drug Landscape (2026). Hemoglobin SS disease with crisis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/hemoglobin-ss-disease-with-crisis. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing