How many drugs treat Heartburn Prevention?

Drug Landscape tracks 3 marketed treatments for Heartburn Prevention (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

What's the most recent regulatory action in Heartburn Prevention?

Most recent: Pepcid — FDA approved.

How do I subscribe to ongoing alerts?

Subscribe to /feed/disease/heartburn-prevention.xml in Feedly / Inoreader. Every regulatory action, PDUFA date, or trial completion in this treatment area lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Heartburn Prevention — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Heartburn Prevention (disease) competitive landscape: 3 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

3 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Heartburn Prevention, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Pepcid	famotidine	Generic (originally Yamanouchi/Merck)	Histamine-2 Receptor Antagonist [EPC]	Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, Solute carrier family 22 member 2	1986-10-01
Tums	calcium carbonate	Generic (multiple manufacturers)	Antacid, Calcium supplement	Gastric acid (direct neutralization)	1930-01-01
Milk of Magnesia	magnesium hydroxide	Generic (multiple manufacturers)	Osmotic laxative, Antacid	Gastric acid (direct neutralization) + osmotic effect in intestine	1880-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

2026-05-12 — Pepcid · FDA · approved · US

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Generic (multiple manufacturers) · 2 drugs in Heartburn Prevention
Generic (originally Yamanouchi/Merck) · 1 drug in Heartburn Prevention

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Heartburn Prevention:

Cite this brief

Drug Landscape (2026). Heartburn Prevention — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/heartburn-prevention. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing