How many drugs treat headache?

Drug Landscape tracks 6 marketed treatments for headache (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

headache — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

headache (disease) competitive landscape: 6 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

6 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating headache, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Excedrin Extra Strength Pain Reliever	NSAID	Haleon Us Holdings	Nonsteroidal Anti-inflammatory Drug [EPC]	Cyclooxygenase	2004-01-01
Immune Support	CORTISONE	Merck	Non-Standardized Plant Allergenic Extract [EPC]		1974-01-01
Addiclenz	ASPARTAME	Deseret Biologicals, Inc.	Standardized Chemical Allergen [EPC]
MEDIQUE APAP EXTRA STRENGTH acetaminophen tablet, film coated	APAP	HF Acquisition Co LLC, DBA HealthFirst
Dmae 1549	DMAE	Professional Complementary Health Formulas
Aspartame/MSG Detox	MALTODEXTRIN	Deseret Biologicals, Inc.	Standardized Chemical Allergen [EPC]

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Deseret Biologicals, Inc. · 2 drugs in headache
HF Acquisition Co LLC, DBA HealthFirst · 1 drug in headache
Haleon Us Holdings · 1 drug in headache
Merck · 1 drug in headache
Professional Complementary Health Formulas · 1 drug in headache

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Cite this brief

Drug Landscape (2026). headache — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/headache. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing