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Gastrointestinal stromal tumor — Treatment Landscape & Competitive Intelligence

Gastrointestinal stromal tumor (disease) competitive landscape: 8 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

8 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Gastrointestinal stromal tumor, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Ayvakit AVAPRITINIB Blueprint Medicines Kinase Inhibitor [EPC] Platelet-derived growth factor receptor alpha 2020-01-01
Stivarga regorafenib Bayer Kinase Inhibitor Bifunctional epoxide hydrolase 2 2012-01-01
Sunitinib Malate sunitinib-malate Pfizer Moderate Risk QT Prolonging Agents 3-phosphoinositide-dependent protein kinase 1 2006-01-01
Sutent Sunitinib Malate Pfizer Small molecule kinase inhibitor Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET 2006-01-01
Sutent sunitinib Pfizer Moderate Risk QT Prolonging Agents 3-phosphoinositide-dependent protein kinase 1 2006-01-01
Gleevec imatinib Novartis Kinase Inhibitor Receptor tyrosine-protein kinase erbB-2 2001-01-01
Jeselhy Pimitespib Taiho Pharmaceutical Co., Ltd Heat shock protein HSP 90-beta
Gleevec Gleevec M.D. Anderson Cancer Center Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, ATP-binding cassette sub-family G member 2, ATP-dependent RNA helicase DDX3X

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Pfizer · 3 drugs in Gastrointestinal stromal tumor
  2. Bayer · 1 drug in Gastrointestinal stromal tumor
  3. Blueprint Medicines · 1 drug in Gastrointestinal stromal tumor
  4. M.D. Anderson Cancer Center · 1 drug in Gastrointestinal stromal tumor
  5. Novartis · 1 drug in Gastrointestinal stromal tumor
  6. Taiho Pharmaceutical Co., Ltd · 1 drug in Gastrointestinal stromal tumor

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Every new regulatory action, PDUFA date, or trial completion in Gastrointestinal stromal tumor:

Cite this brief

Drug Landscape (2026). Gastrointestinal stromal tumor — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/gastrointestinal-stromal-tumor. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing