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Gastrointestinal stromal tumor — Treatment Landscape & Competitive Intelligence
8 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Ayvakit | AVAPRITINIB | Blueprint Medicines | Kinase Inhibitor [EPC] | Platelet-derived growth factor receptor alpha | 2020-01-01 | |
| Stivarga | regorafenib | Bayer | Kinase Inhibitor | Bifunctional epoxide hydrolase 2 | 2012-01-01 | |
| Sunitinib Malate | sunitinib-malate | Pfizer | Moderate Risk QT Prolonging Agents | 3-phosphoinositide-dependent protein kinase 1 | 2006-01-01 | |
| Sutent | Sunitinib Malate | Pfizer | Small molecule kinase inhibitor | Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET | 2006-01-01 | |
| Sutent | sunitinib | Pfizer | Moderate Risk QT Prolonging Agents | 3-phosphoinositide-dependent protein kinase 1 | 2006-01-01 | |
| Gleevec | imatinib | Novartis | Kinase Inhibitor | Receptor tyrosine-protein kinase erbB-2 | 2001-01-01 | |
| Jeselhy | Pimitespib | Taiho Pharmaceutical Co., Ltd | Heat shock protein HSP 90-beta | |||
| Gleevec | Gleevec | M.D. Anderson Cancer Center | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, ATP-binding cassette sub-family G member 2, ATP-dependent RNA helicase DDX3X |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Pfizer · 3 drugs in Gastrointestinal stromal tumor
- Bayer · 1 drug in Gastrointestinal stromal tumor
- Blueprint Medicines · 1 drug in Gastrointestinal stromal tumor
- M.D. Anderson Cancer Center · 1 drug in Gastrointestinal stromal tumor
- Novartis · 1 drug in Gastrointestinal stromal tumor
- Taiho Pharmaceutical Co., Ltd · 1 drug in Gastrointestinal stromal tumor
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Cite this brief
Drug Landscape (2026). Gastrointestinal stromal tumor — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/gastrointestinal-stromal-tumor. Accessed 2026-06-10.
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