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Constipation — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Cholbam | CHOLIC ACID | Mirum | Bile Acid [EPC] | G-protein coupled bile acid receptor 1 | 2015-01-01 | |
| Halflytely | BISACODYL | Braintree | Stimulant Laxative [EPC] | Kappa-type opioid receptor | 2004-01-01 | |
| Renacidin | MAGNESIUM CARBONATE | United Guardian | Vitamin C [EPC] | 1990-01-01 | ||
| Miralax | Macrogol | Braintree | Osmotic Laxative [EPC] | 1984-01-01 | ||
| Prepopik | MAGNESIUM OXIDE | Baxter | magnesium oxide | 1982-01-01 | ||
| Cephulac | LACTULOSE | Sanwa Kagaku Kenkyusho Co., Ltd. | Osmotic Laxative [EPC] | 1976-01-01 | ||
| Micro-K 10 | POTASSIUM CHLORIDE | Nesher Pharms | potassium chloride | Carbonic anhydrase 4 | 1965-01-01 | |
| Colace | docusate sodium | Generic (multiple manufacturers) | Stool softener (surfactant laxative) | N/A (surfactant mechanism) | 1955-01-01 | |
| Milk of Magnesia | magnesium hydroxide | Generic (multiple manufacturers) | Osmotic laxative, Antacid | Gastric acid (direct neutralization) + osmotic effect in intestine | 1880-01-01 | |
| Senna-S | SENNA | HealthLife of USA LLC |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- · 8 drugs in Constipation
- Generic (multiple manufacturers) · 2 drugs in Constipation
- Braintree · 2 drugs in Constipation
- HealthLife of USA LLC · 1 drug in Constipation
- Mirum · 1 drug in Constipation
- Mirum Pharmaceuticals, Inc. · 1 drug in Constipation
- Napp Pharmaceuticals Ltd · 1 drug in Constipation
- Nesher Pharms · 1 drug in Constipation
- OTSUKA ICU MEDCL · 1 drug in Constipation
- Rutgers, The State University of New Jersey · 1 drug in Constipation
- Sanwa Kagaku Kenkyusho Co., Ltd. · 1 drug in Constipation
- The Wellness Center · 1 drug in Constipation
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Cite this brief
Drug Landscape (2026). Constipation — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/constipation. Accessed 2026-06-10.
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