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Constipation — Treatment Landscape & Competitive Intelligence

Constipation (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Constipation, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Cholbam CHOLIC ACID Mirum Bile Acid [EPC] G-protein coupled bile acid receptor 1 2015-01-01
Halflytely BISACODYL Braintree Stimulant Laxative [EPC] Kappa-type opioid receptor 2004-01-01
Renacidin MAGNESIUM CARBONATE United Guardian Vitamin C [EPC] 1990-01-01
Miralax Macrogol Braintree Osmotic Laxative [EPC] 1984-01-01
Prepopik MAGNESIUM OXIDE Baxter magnesium oxide 1982-01-01
Cephulac LACTULOSE Sanwa Kagaku Kenkyusho Co., Ltd. Osmotic Laxative [EPC] 1976-01-01
Micro-K 10 POTASSIUM CHLORIDE Nesher Pharms potassium chloride Carbonic anhydrase 4 1965-01-01
Colace docusate sodium Generic (multiple manufacturers) Stool softener (surfactant laxative) N/A (surfactant mechanism) 1955-01-01
Milk of Magnesia magnesium hydroxide Generic (multiple manufacturers) Osmotic laxative, Antacid Gastric acid (direct neutralization) + osmotic effect in intestine 1880-01-01
Senna-S SENNA HealthLife of USA LLC

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 8 drugs in Constipation
  2. Generic (multiple manufacturers) · 2 drugs in Constipation
  3. Braintree · 2 drugs in Constipation
  4. HealthLife of USA LLC · 1 drug in Constipation
  5. Mirum · 1 drug in Constipation
  6. Mirum Pharmaceuticals, Inc. · 1 drug in Constipation
  7. Napp Pharmaceuticals Ltd · 1 drug in Constipation
  8. Nesher Pharms · 1 drug in Constipation
  9. OTSUKA ICU MEDCL · 1 drug in Constipation
  10. Rutgers, The State University of New Jersey · 1 drug in Constipation
  11. Sanwa Kagaku Kenkyusho Co., Ltd. · 1 drug in Constipation
  12. The Wellness Center · 1 drug in Constipation

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Cite this brief

Drug Landscape (2026). Constipation — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/constipation. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing