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Chronic pain — Treatment Landscape & Competitive Intelligence

Chronic pain (disease) competitive landscape: 6 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

6 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Chronic pain, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Subutex BUPRENORPHINE Purdue Pharma Lp Partial Opioid Agonist mu-opioid receptor, kappa-opioid receptor 1981-01-01
Subutex Buprenorphine Hydrochloride Indivior partial opioid agonist mu-opioid receptor, kappa-opioid receptor 1981-01-01
Opana Er OXYMORPHONE Endo Opioid Agonist Mu-type opioid receptor 1959-01-01
MS Contin morphine sulfate Generic (multiple manufacturers) Opioid analgesic Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor 1941-01-01
Naltrexon Naltrexon Institute of Liver and Biliary Sciences, India Neuronal acetylcholine receptor subunit alpha-7, Cytochrome P450 2D6, Delta-type opioid receptor
Ultram tramadol Janssen Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 1 drug in Chronic pain
  2. Endo · 1 drug in Chronic pain
  3. Generic (multiple manufacturers) · 1 drug in Chronic pain
  4. Indivior · 1 drug in Chronic pain
  5. Institute of Liver and Biliary Sciences, India · 1 drug in Chronic pain
  6. Janssen · 1 drug in Chronic pain
  7. Pfizer · 1 drug in Chronic pain
  8. Purdue Pharma Lp · 1 drug in Chronic pain

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Every new regulatory action, PDUFA date, or trial completion in Chronic pain:

Cite this brief

Drug Landscape (2026). Chronic pain — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/chronic-pain. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing