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Last reviewed 2026-06-10 · How we verify

Chronic idiopathic constipation — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Chronic idiopathic constipation (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Chronic idiopathic constipation, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Pizensy	LACTITOL	Braintree Labs	Osmotic Laxative		2020-01-01
Trulance	PLECANATIDE	Salix	Guanylate Cyclase-C Agonist [EPC]	Tumor necrosis factor	2017-01-01
Linzess	LINACLOTIDE	AbbVie	Guanylate Cyclase-C Agonist [EPC]	Heat-stable enterotoxin receptor	2012-01-01
Amitiza	LUBIPROSTONE	Sucampo Pharma Llc	Chloride Channel Activator [EPC]	Chloride channel protein 2	2006-01-01
Linzess	Linzess	TriHealth Inc.		Heat-stable enterotoxin receptor, Heat-stable enterotoxin receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

· 1 drug in Chronic idiopathic constipation
AbbVie · 1 drug in Chronic idiopathic constipation
Braintree Labs · 1 drug in Chronic idiopathic constipation
Salix · 1 drug in Chronic idiopathic constipation
Sucampo Pharma Llc · 1 drug in Chronic idiopathic constipation
TriHealth Inc. · 1 drug in Chronic idiopathic constipation

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Cite this brief

Drug Landscape (2026). Chronic idiopathic constipation — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/chronic-idiopathic-constipation. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing