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Last reviewed 2026-06-10 · How we verify

Breakthrough Pain in Opioid Tolerant Patients — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Breakthrough Pain in Opioid Tolerant Patients (disease) competitive landscape: 2 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

2 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Breakthrough Pain in Opioid Tolerant Patients, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Duragesic	fentanyl	Johnson & Johnson (Janssen Pharmaceutica)	Synthetic opioid analgesic	D(4) dopamine receptor, Solute carrier family 22 member 1, D(2) dopamine receptor		1968-01-01
Fentanyl (F2)	Fentanyl (F2)	Oslo University Hospital	Synthetic opioid	D(4) dopamine receptor, Solute carrier family 22 member 1, D(2) dopamine receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Johnson & Johnson (Janssen Pharmaceutica) · 1 drug in Breakthrough Pain in Opioid Tolerant Patients
Oslo University Hospital · 1 drug in Breakthrough Pain in Opioid Tolerant Patients

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Cite this brief

Drug Landscape (2026). Breakthrough Pain in Opioid Tolerant Patients — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/breakthrough-pain-in-opioid-tolerant-patients. Accessed 2026-06-10.

Breakthrough Pain in Opioid Tolerant Patients full disease profile — treatment pathway, diagnostics, guidelines
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing