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Last reviewed 2026-06-10 · How we verify

3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency (disease) competitive landscape: 2 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

2 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating 3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	Line of therapy	First approval
Cholbam	CHOLIC ACID	Mirum	Bile Acid [EPC]	G-protein coupled bile acid receptor 1		2015-01-01
Cholbam	Cholbam	Mirum Pharmaceuticals, Inc.		G-protein coupled bile acid receptor 1, Bile acid receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Mirum · 1 drug in 3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency
Mirum Pharmaceuticals, Inc. · 1 drug in 3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency

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Every new regulatory action, PDUFA date, or trial completion in 3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency:

Cite this brief

Drug Landscape (2026). 3-Beta-hydroxy-delta-5-C27-steroid dehydrogenase deficiency — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/3-beta-hydroxy-delta-5-c27-steroid-dehydrogenase-deficiency. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing