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Digoxin Antibodies Fab Fragments — Competitive Intelligence Brief
marketed
Antidote; Digoxin-specific antibody fragment
Digoxin
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Digoxin Antibodies Fab Fragments (Digoxin Antibodies Fab Fragments) — University of Maryland, Baltimore. Digoxin-specific antibody fragments bind to and neutralize circulating digoxin, preventing its toxic cardiac effects.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Digoxin Antibodies Fab Fragments TARGET | Digoxin Antibodies Fab Fragments | University of Maryland, Baltimore | marketed | Antidote; Digoxin-specific antibody fragment | Digoxin | |
| Digoxin immune fab | Digoxin immune fab | National Institute on Aging (NIA) | marketed | Antidote; Immunoglobulin fragment | Digoxin (cardiac glycoside) | |
| Magnesium sulfate and then Digoxin | Magnesium sulfate and then Digoxin | Sunnybrook Health Sciences Centre | phase 3 | Electrolyte supplement and cardiac glycoside combination | Na+/K+-ATPase (digoxin); magnesium-dependent ion channels and enzymes (magnesium sulfate) | |
| Antizol | FOMEPIZOLE | Par Pharm Inc | marketed | Antidote [EPC] | Alcohol dehydrogenase | 1997-01-01 |
| Cyanokit | HYDROXOCOBALAMIN | Btg Intl | marketed | Antidote | 1978-01-01 | |
| Acetadote | Acetylcysteine | Bristol-Myers Squibb | marketed | Antidote | Glutathione levels; reactive metabolite of acetaminophen | 1963-01-01 |
| Actidose Aqua | Actidose Aqua | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Adsorbent antidote |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Acetadote · 8148356 · Formulation · US
- — Acetadote · 9327028 · Method of Use · US
- — Acetadote · 8722738 · Method of Use · US
- — Acetadote · 8747894 · Formulation · US
- — Acetadote · 9561204 · Method of Use · US
- — Acetadote · 9427421 · Formulation · US
Sponsor landscape (Antidote; Digoxin-specific antibody fragment class)
- University of Maryland, Baltimore · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Digoxin Antibodies Fab Fragments — Competitive Intelligence Brief. https://druglandscape.com/ci/digoxin-antibodies-fab-fragments. Accessed 2026-05-17.
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