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didanosine + lamivudine + efavirenz — Competitive Intelligence Brief
marketed
Antiretroviral combination therapy (NRTI + NNRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
didanosine + lamivudine + efavirenz (didanosine + lamivudine + efavirenz) — Clinical Trial Agency of HIV Study Group. This combination of three antiretroviral drugs inhibits HIV replication by blocking reverse transcriptase and integrase enzymes required for viral reproduction.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| didanosine + lamivudine + efavirenz TARGET | didanosine + lamivudine + efavirenz | Clinical Trial Agency of HIV Study Group | marketed | Antiretroviral combination therapy (NRTI + NNRTI) | HIV reverse transcriptase | |
| Once-daily ABC+3TC | Once-daily ABC+3TC | Medical Research Council | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| Abacavir/Lamivudine | Abacavir/Lamivudine | GlaxoSmithKline | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| Dolutegravir/Lamivudine as a single pill | Dolutegravir/Lamivudine as a single pill | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| nucleoside reverse transcriptase inhibitors | nucleoside reverse transcriptase inhibitors | French National Agency for Research on AIDS and Viral Hepatitis | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| All licensed antiretroviral medications | All licensed antiretroviral medications | University of Minnesota | marketed | Antiretroviral agents (multiple classes: NRTIs, NNRTIs, PIs, INSTIs, entry inhibitors) | Multiple (HIV reverse transcriptase, HIV protease, HIV integrase, CCR5, CXCR4, gp120/gp41) | |
| AZT+3TC+IDV+RTV | AZT+3TC+IDV+RTV | Hospital Clinic of Barcelona | marketed | Antiretroviral combination therapy (NRTI + PI) | HIV reverse transcriptase; HIV protease |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NRTI + NNRTI) class)
- GlaxoSmithKline · 2 drugs in this class
- Clinical Trial Agency of HIV Study Group · 1 drug in this class
- Hospital Clinic of Barcelona · 1 drug in this class
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · 1 drug in this class
- National Center for AIDS/STD Control and Prevention, China CDC · 1 drug in this class
- Peking Union Medical College Hospital · 1 drug in this class
- Sheba Medical Center · 1 drug in this class
- Azienda Ospedaliera San Gerardo di Monza · 1 drug in this class
- University of KwaZulu · 1 drug in this class
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Cite this brief
Drug Landscape (2026). didanosine + lamivudine + efavirenz — Competitive Intelligence Brief. https://druglandscape.com/ci/didanosine-lamivudine-efavirenz. Accessed 2026-05-18.
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